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Tyrosine: Effects on catecholamine release.
Brain Res. Bull., 21:473-477, 1988.
Processes that couple amino acid availability to neurotransmitter synthesis and release.
Amino Acid Availability and Brain Function in Health and Disease, (G. Huether, ed.) Springer-Verlag Berlin Heidelberg, NATO ASI Series, Vol. H20: pp.117-36, 1988.
Feeding-associated alterations in striatal neurotransmitter release.
Psychobiology of Human Eating Disorders: Preclinical and Clinical Perspectives, (L.H. Schneider, S.J. Cooper, K.A. Halmi, eds.) New York Acad. Sci., 575: 596-598, 1989.
Precursor Control of catecholamine metabolism.
Amino Acids in Psychiatric Disease, (M.A. Richardson, ed.) American Psychiatric Press, Inc., Washington: Chapter 1, pp.1-29, 1990.
Effect of cyclic changes in environmental lighting and ambient temperature on the daily rhythm in melatonin excretion by rats.
Brain Res., 163:111-120, 1979.
Changes in catecholamine excretion after short-term tyrosine ingestion in normally fed human subjects.
Amer. J. Clin. Nutr., 34:82-87, 1981.
Effect of acute administration of neutral and other amino acids on urinary excretion of catecholamines.
Life Sci., 30:739-746, 1982.
Studies on the mechanism by which tyrosine raises urinary catecholamines.
Biochem. Pharm., 31(22):3577-3580, 1982.
Effect of dietary proteins and carbohydrates on urinary and sympathoadrenal catecholamines.
Neurochem. Int., 7(2):271-277, 1985.
Cytidine(5’)Diphosphocholine enhances the ability of haloperidol to increase dopamine metabolites in the striatum of the rat and to diminish stereotyped behavior induced by apomorphine.
Neuropharmacology, 23(12A):1403-1406, 1984.
Oral cytidine 5’-diphosphate choline administration to rats increases brain phospholipid levels.
Alzheimer’s Disease, Amyloid Precursor Proteins, Signal Transduction, and Neuronal Transplantation, (Nitsch, R.M., Growdon, J.H., Corkin, S., and Wurtman, R.J., eds.) Ann. N.Y. Acad. Sci., 695: 318-320, 1993.
Effect of pyridoxine on the depletion of tissue pyridoxal phosphate by carbidopa.
Metabolism, 27(7):771-779, 1978.
Tyrosine loading enhances catecholamine excretion by rats.
J. Neural Transmission, 49:31-43, 1980.
Elevation of urinary catecholamines and their metabolites following tyrosine administration in humans.
Biol. Psych., 17(7):781-790, 1982.
5-Hydroxytryptophan raises plasma 5-HTP levels in humans and rats and suppresses food intake by hypophagic and stressed rats.
J. Pharm., Biochem. Behav.,, 77:137-143, 2004.
Mechanism of changes in brain norepinephrine metabolism after ovariectomy.
Neuroendocrinology, 6:265-273, 1970.
Increased turnover of 3H-norepinephrine in rat brain following castration or treatment with ovine follicle-stimulating hormone.
Endocrinology, 84(6):1489-1492, 1969.
Regional uptake of 3H-melatonin from blood or cerebrospinal fluid by rat brain.
Nature, 221(5179):474-475, 1969.
Stimulation of hydroxyindole—methyl transferase activity in hamster pineal glands by blinding or continuous darkness.
Endocrin., 82:1245-1256, 1968.
Norepinephrine: Turnover in rat brains after gonadectomy.
Science, 159:1245, 1968.
Brain monoamines and endocrine function.
Frontiers in Neuroendocrinology, (L. Martini and W.F. Ganong, eds.) Oxford University Press, New York: 45-66, 1971.
Control of membrane phosphatidylcholine biosynthesis by diacylglycerol levels in neuronal cells undergoing neurite outgrowth.
Proc. Natl. Acad. Sci., 94:11946-11950, 1997.
Mini-review: How is membrane phospholipid biosynthesis controlled in neural tissues?.
J. Neurosci. Res., 51:667-674, 1998.
Increased expression of amyloid precursor protein and amyloid precursor-like protein 2 during trophic factor withdrawal-induced death of neuronal PC12 cells.
Molecular Brain Res., 56:169-177, 1998.
Effect of 5-HT2C serotonin agonist, dexnorfenfluramine, on amyloid precursor protein metabolism in Guinea pigs.
Brain Research, 951:135-140, 2002.
An animal model of antipsychotic-induced weight gain.
Behav. Brain Res., 152:121-127, 2004.
Stimulation of C14-melatonin synthesis from C14-tryptophan by noradrenaline in rat pineal in organ culture.
Proc. Nat. Acad. Sci., 62:544-549, 1969.
Control of hydroxyindole-O-methyltransferase activity in the rat pineal gland by environmental lighting.
J. Biol. Chem., 240:949-954, 1965.
Melatonin synthesis in the hen pineal gland and its control by light.
Nature, 201(4924):1134, 1964.
Melatonin, a pineal hormone: Biosynthesis, metabolism, and actions.
The pineal gland: A biological clock.
Problemes Actuels d’Endocrinologie et de Nutrition, 10:201-212, 1966.
Effects of cardiovascular drugs on the physiological disposition of norepinephrine.
Heart Bulletin, 16:49-53, 1967.
Fate of norepinephrine in sympathetic neuron and the effect of cardiovascular drugs.
New York State Journal of Med., 68(1):252-256, 1968.
Photic and neural control of indoleamine metabolism in the rat pineal gland.
Advances in Pharmacology, 6A:157-166, 1968.
Differential effect of CDP-choline on brain cystolic choline levels in younger and older subjects as measured by proton magnetic resonance spectroscopy.
Psychopharmacology, 127:88-94, 1996.
Dexfenfluramine enhances striatal dopamine release in conscious rats via a serotoninergic mechanism.
Journal Pharm. Exp. Ther., 284:991-997, 1998.
Effects of phentermine on striatal dopamine and serotonin release in conscious rats: In vivo microdialysis.
Intl. Journal Obesity, 22:325-328, 1998.
Effects of fenfluramine and phentermine (fen-phen) on dopamine and serotonin release in rat striatum: In vivo microdialysis study in conscious animals.
Brain Res., 813:67-72, 1998.
Sibutramine, a serotonin uptake inhibitor, increases dopamine concentrations in rat striatal and hypothalamic extracellular fluid.
Neuropharmacology, 39:2352-2359, 2000.
Matters arising – Striatal serotonin receptors and dopamine release.
Response to Lucas and Sampinato. Journal Neurochem., 75(2):886, 2000.
Control of adrenal medullary protein synthesis by corticosteroids.
Biochem. Biophys. Acta, 299:337-343, 1973.
Preliminary report of the committee on phototherapy in the newborn infant.
Journal Pediatrics, 84(1):135-143, 1974.
A balanced carbohydrate: Protein diet in the management of Parkinson's disease.
Neurology, 41:1295-1297, 1991.
Abnormal phospholipid turnover and pathophysiology of Alzheimer's disease.
Bulletin of Clin. Neurosci., 55:91-98, 1990.
Autocannibalism of membrane choline-phospholipids: Physiology and pathology.
Psychopharm. Bull., 22(3):781-786, 1986.
Phosphatidylcholine as a precursor of choline for acetylcholine synthesis.
J. Neural Transm., 24(Suppl):247-259, 1987.
Levels of phospholipid catabolic intermediates, glycerophosphocholine and glycerophosphoethanolamine, are elevated in brains of Alzheimer’s disease but not of Down’s syndrome patients.
Brain Res., 536:240-244, 1990.
Synthesis of lecithin (phosphatidylcholine) from phosphatidyl-ethanolamine in bovine brain.
Brain Res., 179:319-327, 1979.
Developmental changes in the activity of phosphatidylethanolamine N-methyltransferases in rat brain.
Biochem. J., 232:505-511, 1985.
Choline biosynthesis by a preparation enriched in synaptosomes from rat brain.
Nature, 290(5085):417-418, 1981.
Choline and cholinergic neurons.
Science, 221:614-620, 1983.
Consumption of a high dietary dose of monosodium glutamate fails to affect extracellular glutamate levels in the hypothalamic arcuate nucleus of adult rats.
Brain Res., 736:76-81, 1996.
Effects of systemic or oral ad libitum monosodium glutamate administration on striatal glutamate release, as measured using microdialysis in freely moving rats.
Brain Res., 660:337-340, 1994.
Choline-induced attenuation of morphine analgesia in the rat.
Commun. Psychopharm., 1:519-523, 1977.
B-endorphin administration increases hippocampal acetylcholine levels.
Life Sci., 24:1799-1804, 1979.
Choline reverses naloxone-induced decreases in hippocampal acetylcholine content and suppresses escape behavior in opiate- dependent rats.
Brain Res., 210:479-484, 1981.
Corticotropin regulates transsynaptically the activity of septohippocampal cholinergic neurons.
Nature, 289(5793):75-76, 1981.
Septohippocampal cholinergic neurons are regulated trans-synaptically by endorphin and corticotropin neuropeptides.
J. Neurosci., 2(9):1316-1321, 1982.
Effect of exogenous melatonin on sleep - a meta-analysis of 14 controlled clinical trials.
Sleep Medicine Reviews, 9:41-50, 2005.
The circadian rhythm of plasma melatonin during the normal menstrual cycle and in amenorrheic women.
J. Clin. Endocrin. Metab., 66(5):891-895, 1988.
Possible contribution of melatonin to the timing of the luteinizing hormone surge.
New Eng. J. Med., 316:1550-1551, 1987.
Melatonin in human preovulatory follicular fluid.
J. Clin. Endocrin. Metab., 64(4):865-867, 1987.
The pineal gland: Its possible roles in human reproduction.
Obstetrical & Gynecological Survey, 43(4):197-207, 1988.
D-Fenfluramine suppresses the increased calorie and carbohydrate intakes and improves the mood of women with premenstrual depression.
Obstet. & Gynecol., 76(2):296-391, 1990.
Interactions of 3,4-diaminopyridine and choline in stimulating acetylcholine release and protecting membrane phospholipids.
Brain Res., 541:1-6, 1991.
Tetrahydroaminoacridine but not 4-aminopyridine inhibits high-affinity choline uptake in striatal and hippocampal synaptosomes.
Brain Res., 482:371-375, 1989.
4-aminopyridine increases acetylcholine release without diminishing membrane phosphatidylcholine.
J. Neurochem., 54(4):1302-1309, 1990.
Plasma amino acid levels in obesity: Effects of insulin resistance.
Amino Acids in Health and Diseases: New Perspectives (S. Kaufman, ed.) Alan R. Liss, Inc., New York, pp.369-382, 1987.
Plasma amino acids and insulin levels in obesity: Response to carbohydrate intake and tryptophan supplements.
Metabolism, 37(7):672-676, 1988.
Plasma amino acid concentrations in healthy elderly men and women.
Am. J. Clin. Nutr., 53:1249-1252, 1991.
Plasma amino acid levels after single-dose aspartame consumption in phenylketonuria, mild hyperphenylalaninemia, and heterozygous state for phenylketonuria.
J. Pediatrics, 109(4):668-671, 1986.
Differential effects of insulin resistance on leucine and glucose kinetics in obesity.
Metabolism, 40(1):51-58, 1991.
Giving uridine plus docosahexaenoic acid supplementation orally to rat dams during gestation and nursing increases synaptic elements in brains of weanling pups.
Developmental Neuroscience, 31:181-192, 2009.
Evidence for the existence of pyrimidinergic transmission in rat brain.
Neuropharmacology, 91:77-86, 2015.
Restorative effects of uridine plus docosahexaenoic acid in a rat model of Parkinson's disease.
Neuroscience Research, 62:206-209, 2008.
Oral Uridine-5'-monophosphate (UMP) increases brain CDP-choline levels in gerbils.
Brain Research, 1058:101-108, 2005.
Oral administration of circulating precursors for membrane phosphatides can promote the synthesis of new brain synapses.
Alzheimer's & Dementia, 4:S153-S168, 2008.
Aromatic amino acids in the brain.
Handbook of Neurochemistry and Molecular Neurobiology, Third ed., vol. 6, Chpt. 4, pp. 60-97, (A. Lajtha, ed.), Springer-Verlag, Berlin, Heidelberg, 2007.
Chronic administration of docosahexaenoic acid or eicosapentaenoic acid, but not arachidonic acid, alone or in combination with uridine increases brain phosphatide and synaptic proteins levels in gerbils.
Neuroscience, 148:421-431, 2007.
Fate of intracisternally injected melatonin in the rat brain.
Neuroendocrin., 12:30-40, 1973.
Control of the rat pineal gland by light spectra.
Proc. Nat. Acad. Sci., 69(8):2003-2005, 1972.
Action spectra for effects of light on hydroxyindole-O-methyl transferases in rat pineal, retina and harderian gland.
Endocrin., 91(4):877-886, 1972.
Binding of melatonin to human and rat plasma proteins.
Endocrin., 91(5):1213-1218, 1972.
Hydroxyindole-O-methyl transferases in rat pineal, retina and harderian gland.
Endocrinology, 91(1):247-252, 1972.
Effects of L-dopa on norepinephrine metabolism in the brain.
Proc. Nat. Acad. Sci., 68(3):662-666, 1971.
Ther., 178(1):8-19, 1971.
Development of tolerance in rats to the hypothermic effects of d-amphetamine and apomorphine.
Life Sci., 14:483-488, 1974.
Short-term variations in diet composition change the pattern of spontaneous motor activity in rats.
Science, 213:676-678, 1981.
Probable nutritional basis for effect of estradiol on rat liver catechol-O-methyl transferase.
Life Sci., 11(I):581-585, 1972.
An inhibitory effect of melatonin on the estrous phase of the estrous cycle of the rodent.
Endocrin., 75(2):238-242, 1964.
Decreased brain choline uptake in older adults. An in vivo proton magnetic resonance spectroscopy study.
JAMA, 274(11):902-907, 1995.
Brain acetylcholine: Control by dietary choline.
Science, 191:561-562, 1976.
Brain acetylcholine: Increase after systemic choline administration.
Life Sci., 16:1095-1102, 1975.
Some clinical, biochemical, and physiological actions of the pineal gland.
Ann. Int. Med., 61(6):1144-1161, 1964.
Influence of feeding habits and adrenal cortex on diurnal rhythm of hepatic tyrosine transaminase activity.
Proc. Soc. Exp. Biol. Med., 133(2):460-462, 1970.
Effects of ingestion of a carbohydrate-fat meal on the levels and synthesis of 5-hydroxyindoles in various regions of the rat central nervous system.
Journal Neurochem., 25:825-829, 1975.
The relation between urinary 5-hydroxyindoleacetic acid levels and the ratio of tryptophan to other large neutral amino acids placed in the stomach.
Metabolism, 28(8):820-827, 1979.
Caffeine alters plasma adenosine levels.
Nature, 389:136, 1997.
Endogenous adenosine and hemorrhagic shock: Effects of caffeine administration or caffeine withdrawal.
Proc. Natl. Acad. Sci., 85:4483-4485, 1988.
Spinal cord noradrenergic neurons are activated in hypotension.
Brain Res., 375:210-213, 1986.
Tyrosine's vasoactive effect in the dog shock model depends on the animal's starting blood pressure.
J. Neural Trans., 58:69-74, 1983.
Effects of hemorrhagic hypotension on tyrosine concentrations in rat spinal cord and plasma.
Neurochem. Int., 12(3):291-295, 1988.
Tyrosine increases blood pressure in hypotensive rats.
Science, 212:559-560, 1981.
Tyrosine's pressor effect in hypotensive rats is not mediated by tyramine.
Life Sci., 35(11):1207-1212, 1984.
Tyrosine accelerates catecholamine synthesis in hemorrhaged hypotensive rats.
Brain Res., 333:81-84, 1985.
Alanine increases blood pressure during hypotension.
Pharmacol. Toxicol., 66:415-416, 1990.
Exercise and neuromodulators: Choline and acetylcholine in marathon runners.
Int. Journal Sports Med., 13:S141-S142, 1992.
Decreased plasma choline concentrations in marathon runners.
New Eng. J. Med., 315:892, 1986.
Effects of running the Boston marathon on plasma concentrations of large neutral amino acids.
Journal Neural Transm., 76:65-71, 1989.
Advances in endocrinology.
The Practitioner, 199:485-497, 1967.
Melatonin and its precursors in Y79 human retinoblastoma cells: Effect on sodium butyrate.
Brain Res., 561:274-278, 1991.
L-tyrosine ameliorates some effects of lower body negative pressure stress.
Physiol. Behav., 57(2):223-230, 1995.
Effect of pharmacological daytime doses of melatonin on human mood and performance.
Psychopharmacology, 112:490-496, 1993.
Effects of illumination on human nocturnal serum melatonin levels and performance.
Physiol. & Beh., 53:153-160, 1993.
Effect of inducing nocturnal serum melatonin concentrations in daytime on sleep, mood, body temperature, and performance.
Proc. Natl. Acad. Sci., 91:1824-1828, 1994.
Effects of systemic L-tyrosine on dopamine release from rat corpus striatum and nucleus accumbens.
Brain Res., 452:378-380, 1988.
Phenylalanine administration influences dopamine release in the rat's corpus striatum.
Neurosci. Lett., 93:91-95, 1988.
Dopamine release in rat striatum: Physiological coupling to tyrosine supply.
Journal Neurochem., 52(5):1449-1454, 1989.
Effects of subchronic pretreatment with D-fenfluramine or p-chloroamphetamine on [3H]inositolmonophosphate accumulation in rat cortical miniprisms.
Brain Res., 665:107-114, 1994.
A1 and A2-selective adenosine antagonists: In Vivo characterization of cardiovascular effects.
J. Pharmacol. Exp. Ther., 242(3):882-887, 1987.
Antagonism of the cardiovascular effects of adenosine by caffeine or 8-(p-Sulfophenyl)theophylline. Journal Pharmacol.
Exp. Therap., 240(2):428-432, 1987.
Adenosine affects sympathetic neurotransmission at multiple sites in vivo.
J. Pharmacol. Exp. Ther., 236(2):350-355, 1986.
Potentiation by choline of basal and electrically evoked acetylcholine release, as studied using a novel device which both stimulates and perfuses rat corpus striatum.
Brain Res., 607:177-184, 1993.
Regulated secretion of ß-amyloid precursor protein in rat brain.
J. Neurosci., 15(11):7442-7451, 1995.
Choline's phosphorylation in rat striatal slices is regulated by the activity of cholinergic neurons.
Brain Res., 723:90-99, 1996.
Diurnal variations in plasma insulin concentrations in normal and cirrhotic subjects: Effect of dietary protein.
Journal of Neural Trans., Suppl. 14:133-142, 1978.
Correlations between brain tryptophan and plasma neutral amino acid levels following food consumption in rats.
Life Sci., 13:517-524, 1973.
Daily variations in the concentrations of individual amino acids in rat plasma.
Life Sci., 10(1):813-819, 1971.
Brain tryptophan in rats on a high fat diet.
Nature, 265(5591):277, 1977.
Letter to the Editor.
New Eng. Journal Med., 303:158, 1980.
Diurnal variations in plasma neutral amino acid concentrations among patients with cirrhosis: Effect of dietary protein.
Am. J. Clin. Nutr., 32:1923-1933, 1979.
Diurnal variations in plasma concentrations of tryptophan, tyrosine, and other neutral amino acids: Effect of dietary protein intake.
Am. J. Clin. Nutr., 32:1912-1922, 1979.
Brain serotonin content: physiological dependence on plasma tryptophan levels.
Science, 173:149-152, 1971.
Effect of chronic corn consumption on serotonin content of rat brain.
Nature New Biol., 234(45):62-64, 1971.
Brain serotonin content: Increase following ingestion of carbohydrate diet.
Science, 174:1023-1025, 1971.
Elevation of plasma tryptophan by insulin in rat.
Metabolism, 21(4):337-342, 1972.
Brain serotonin content: Physiological regulation by plasma neutral amino acids.
Science, 178:414-416, 1972.
Nutrition and the brain.
Sci. Amer., 230(2):84-91, 1974.
Increase in striatal choline acetyltransferase activity after choline administration.
Brain Res., 165:358-361, 1979.
Effects of lumbar sympathectomy on the uterine uptake of catecholamines.
Nature, 203:938-939, 1964.
Daily rhythms in hepatic polysome profiles and tyrosine transaminase activity: Role of dietary protein.
Proc. Nat. Acad. Sci., 64(2):677-682, 1969.
Some sources of error in the Akerfeldt test for serum oxidative activity.
Proc. Soc. Exp. Biol. Med., 97:478-480, 1958.
Effects of methiothepin on changes in brain serotonin release induced by repeated administration of high doses of anorectic serotoninergic drugs.
Brain Res., 588(1):67-74, 1992.
Persistent blockade of potassium-evoked serotonin release from rat frontocortical terminals after fluoxetine administration.
Brain Res., 540:325-330, 1991.
Tyrosine for depression.
Journal Psychiat. Res., 17(2):175-180, 1982.
Tyrosine for the treatment of depression.
Am. J. Psychiatry, 137(5):622-623, 1980.
L-tyrosine in depression.
Lancet, 316(8199):863-864, 1980.
The effects of tyrosine and other nutrients on neurotransmitter synthesis in the brain and retina.
Retina, 2(4):332-340, 1982.
Tyrosine administration enhances dopamine synthesis and release in light-activated rat retina.
J. Neural Trans., 56:153-160, 1983.
Physiological control of brain catechol synthesis by brain tyrosine concentration.
Biochem. Pharm., 26:1137-1142, 1977.
Changes in brain levels of acidic, basic, and neutral amino acids after consumption of single meals containing proportions of protein.
J. Neurochem., 41(4):1016-1021, 1983.
Elevation of plasma tyrosine after a single oral dose of L-tyrosine.
Life Sci., 25:265-271, 1979.
Physiological disposition of H3-norepinephrine in the developing rat.
Journal Pharmacol. Exp. Ther., 146(1):48-53, 1964.
Release of endogenous dopamine from the superfused rabbit retina in vitro: Effect of light stimulation.
Brain Res., 452:393-395, 1988.
Flow of blood to the pineal body of the rat.
Nature, 203:87, 1964.
Effects of oral choline administration on serum and CSF choline levels in patients with Huntington's Disease.
J. Neurochem., 28:229-231, 1977.
Treatment of brain disease with dietary precursors of neurotransmitters.
Ann. Int. Med., 88(3):337-339, 1977.
Huntington’s Disease: Clinical and chemical effects of choline administration.
Annals of Neurology, 1(5):418-422, 1977.
Lecithin can suppress tardive dyskinesia.
New Eng. J. Med., 298:1029-1030, 1978.
Oral choline administration to patients with tardive dyskinesia.
New Eng. Journal Med., 297:524-527, 1977.
Effects of oral L-tyrosine administration on CSF tyrosine and homovanillic acid levels in patients with Parkinson's disease.
Life Sci., 30:827-832, 1982.
L-threonine in the treatment of spasticity.
Clin. Neuropharm., 14(5):403-412, 1991.
Oral choline administration to patients with Huntington's disease.
In: Advances in Neurology, A. Barbeau, N. Wexler, and T.N. Chase, eds.) Raven Press, New York, Vol. 23:765-776, 1979.
Dietary influences on the synthesis of neurotransmitters in the brain.
Nutrition Reviews, 37(5):129-136, 1979.
Nutrients and neurotransmitters.
The use of choline and lecithin in Alzheimer’s disease.
Weiss). New Eng.
Journal Med., 297:1236, 1978.
A nutritional approach to ameliorate altered phospholipid metabolism in AD.
A nutritional approach to ameliorate altered phospholipid metabolism in Alzheimer's disease.
Journal of Alzheimer's Disease, 41:715-717, 2014.
Long-term administration of L-DOPA does not damage dopaminergic neurons in the mouse.
Neurology, 31:1194-1195, 1981.
Circling behavior in rats with partial, unilateral nigro-striatal lesions: Effect of amphetamine, apomorphine, and DOPA.
Pharmacol. Biochem. Behavior, 12:185-188, 1980.
Partial lesions of the dopaminergic nigrostriatal system in rat brain: Biochemical characterization.
Brain Res., 195:123-137, 1980.
The decarboxylation of DOPA in the Parkinsonian brain: In vivo studies on an animal model.
Journal Neur. Trans., Suppl. 16:95-101, 1980.
The site of dopamine formation in rat striatum after L-Dopa administration.
J. Pharmacol. Exp. Ther., 217(1):189-197, 1981.
The treatment of obesity by carbohydrate deprivation suppresses plasma tryptophan and its ratio to other large neutral amino acids.
Journal Neur. Trans., 57:187-195, 1983.
Tryptophan administration may enhance weight loss by some moderately obese patients on a protein-sparing modified fast (PSMF) diet.
Int. J. Eating Disorders, 4:281-292, 1985.
NG108-15 Hybrid cells take up but do not synthesize serotonin.
Neurochem. Int., 10(2):185-189, 1987.
Effect of (+)-or(-)-enantiomers of fenfluramine or nonfenfluramine on nutrient selection by rats.
Journal Pharm. Pharmacol., 34:18-21, 1982.
Increase in hippocampal acetylcholine after choline administration.
Brain Res., 125:383-385, 1977.
Relations between dietary choline or lecithin intake, serum choline levels, and various metabolic indices.
Metabolism, 27(8):953-960, 1978.
Lecithin consumption increases acetylcholine concentrations in rat brain and adrenal gland.
Science, 202:223-225, 1978.
Dihydroxyphenylalanine in rat food containing wheat and oats.
Science, 175:761-762, 1972.
Effect of selective destruction of central and peripheral catecholamine-containing neurons with 6-hydroxydopamine on catecholamine excretion in the rat.
Br. J. Pharmac., 50:265-270, 1974.
Excretion of catecholamines and catecholamine metabolites in kwashiorkor.
Am. Journal Clin. Nutr., 26:205-210, 1973.
Synthesis of DOPA in rat stomach following ingestion of cereals.
Metabolism, 23(1):25-31, 1974.
Cereal Ingestion and catecholamine excretion.
Metabolism, 23(1):33-41, 1974.
A role for base exchange in cellular calcium signaling? Annals New York Acad.
Sci. (3rd Symposium on Cellular Signal Transduction), 494:114-116, 1987.
Presence of base-exchange activity in rat brain nerve endings: Dependence on soluble substrate concentrations and effect of cations.
J. Neurochem., 50:156-162, 1988.
Calcium-dependent incorporation of choline into phosphatidylcholine (PC) by base-exchange in rat brain membranes occurs preferentially with phospholipid substrates containing docosahexaenoic acid (22:69(n — 3 )).
Biochimica et Biophysica Acta, 1046:185-188, 1990.
Chronic administration of DHA and UMP improves the impaired memory of environmentally impoverished rats.
Behavioural Brain Research, 191:11-16, 2008.
Dietary uridine enhances the improvement in learning and memory produced by administering DHA plus choline to gerbils.
FASEB, 22:3938-3946, 2008.
Effects of injection of bovine pineal extract on the nuclei of rat pineal parenchymal cells.
Nature, 186:393-394, 1960.
Rat liver N-acetyltransferase; Inhibition by melatonin.
Biochem. Pharmacol., 25:977-978, 1976.
Cholinesterases in cerebrospinal fluid correlations with clinical measures in Alzheimer’s disease.
Journal Neurol. Sci., 72:121-129, 1986.
Activation of protein kinase C inhibits cellular production of the amyloid ß-protein.
J. Biol. Chem., 268(31):22959-22962, 1993.
Adenylate cyclase activity in Bovine adrenal medulla.
Endocrin., 94(2):591-593, 1974.
Rapid accumulation of H3-serotonin in brains of rats receiving intraperitoneal H3-tryptophan: Effects of 5,6-dihydroxytryptamine or female sex hormones.
Journal Neur. Trans., 34:111-124, 1973.
Sex-dependent increase in pineal hydroxyindole-O-methyl transferase activity after a single intraventricular injection of 6-hydroxydopamine to newborn rats.
Neuroendocrin., 11:274-283, 1973.
Time-dependent changes in brain 3H-norepinephrine disappearance caused by L-dopa administration.
Life Sci., 11(1):713-721, 1972.
Release of norepinephrine from rat hypothalamic slices: Effects of desipramine and tyrosine.
Brain Res., 423:391-394, 1987.
Choline enhances scopolamine-induced acetylcholine release in dorsal hippocampus of conscious, freely-moving rats.
Life Sci., 56(1):45-49, 1995.
Failure of decreased serotonin uptake or monoamine oxidase inhibition to block the acceleration in brain 5-hydroxyindole synthesis that follows food consumption.
Journal Neur. Trans., 37:25-32, 1975.
Mechanisms by which quipazine, a putative serotonin receptor agonist, alters brain 5-hydroxyindole metabolism.
Neuropharmacol., 15:529-534, 1976.
Thyroid state and brain monoamine metabolism.
Endocrin., 97(5):1332-1335, 1975.
Ther., 195(2):257-264, 1975.
Urinary melatonin rhythms during sleep deprivation in depressed patients and normals.
Life Sci., 20:1501-1508, 1977.
Caffeine potentiates the enhancement by choline of striatal acetylcholine release.
Life Sci., 51:1597-1601, 1992.
Effects of systemic carbidopa on dopamine synthesis in rat hypothalamus and striatum.
Journal Neural Transm. [P-D Sect], 4:143-154, 1992.
Effects of COMT inhibitors on striatal dopamine metabolism: A microdialysis study.
Brain Res., 597:241-249, 1992.
Effects of catechol-O-methyltransferase inhibitors and L-3,4-dihydroxyphenylalanine with or without carbidopa on extracellular dopamine in rat striatum.
J. Neurochem., 60(1):137-144, 1993.
Effects of two diketopiperazines, Cyclo (His-Pro) and Cyclo (Asp-Phe), on striatal dopamine: A microdialysis study.
Brain Res. Bull., 32:667-672, 1993.
Nutrition and Alzheimer's disease: pre-clinical concepts.
European Journal of Neurology, 16 (Supplement 1):12-18, 2009.
Bingeing behavior and plasma amino acids: A possible involvement of brain serotonin in bulimia nervosa.
Psychiat. Res., 23:31-43, 1988.
Mineral homeostasis in obesity: Effects of euglycemic hyperinsulinemia.
Metabolism, 40(7):707-713, 1991.
Res., 61:166-179, 1991.
Selective effects of CGS 10686B, d1-fenfluramine or fluoxetine on nutrient selection.
Physiol. Behav., 42:319-322, 1988.
Carbachol and naloxone synergistically elevate dopamine release in rat striatum: An in vivo microdialysis study.
Brain Res., 613:288-290, 1993.
Enhancement of free fatty acid incorporation into phospholipids by choline plus cytidine.
Brain Res., 822:52-59, 1999.
Flow of uterine blood, and the oestrous cycle.
Nature, 199:386-387, 1963.
Systemic administration of thyrotropin-releasing hormone enhances striatal dopamine release in vivo.
Brain Res., 536:347-352, 1990.
Effect of D-fenfluramine on serotonin release in brains of anaesthetized rats.
Brain Res., 504:258-263, 1989.
In vivo synthesis of phosphatidylcholine in rat brain via the phospholipid methylation pathway.
Brain Res., 419:131-140, 1987.
Molecular composition of the phosphatidylcholines produced by the phospholipid methylation pathway in rat brain in vivo.
Biochem. J., 244:325-330, 1987.
Rotational behavior in gerbils following unilateral common carotid artery ligation.
Journal Neural Trans., 36:83-89, 1975.
Brain catecholamines and cerebral blood flow.
Life Sci., 16(4):475-486, 1975.
Decrease in neostriatal blood flow after D-amphetamine administration or electrical stimulation of the substantia nigra.
Brain Res., 135:76-86, 1977.
Brain H3-catecholamine metabolism in experimental cerebral ischemia.
Neurology, 25(5):483-485, 1975.
Stimulation of amyloid precursor protein synthesis by adrenergic receptors coupled to cAMP formation.
Proc. Natl. Acad. Sci., 94:5422-5426, 1997.
Prostaglandin E2 stimulates amyloid precursor protein gene expression: Inhibition by immunosuppressants.
J. Neurosci., 19(3):940-947, 1999.
Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors.
Proc. Natl. Acad. Sci., 92:8083-8087, 1995.
Metabotropic glutamate receptors increase amyloid precursor protein processing in astrocytes: Inhibition by cyclic AMP.
J. Neurochem., 68(5):1830-1835, 1997.
Relationship between pituitary ACTH content and hypothalamic catecholamines in the rat.
Res. Exp. Med., 189:289-293, 1989.
Increased release of brain serotonin reduces vulnerability to ventricular fibrillation in the cat.
Journal Cardiovas. Pharmacol., 10:389-397, 1987.
Neurochemical and behavioral consequences of acute, uncontrollable stress: Effects of dietary tyrosine.
Brain Res., 303:215-223, 1984.
Dopamine stimulation of phosphatidylcholine (lecithin) biosynthesis in rat brain neurons.
Proc. Natl. Acad. Sci., 80:2063-2066, 1983.
Nerve growth factor stimulates diacylglycerol de novo synthesis and phosphatidylinositol hydrolysis in pheochromocytoma cells.
Brain Res., 803:44-53, 1998.
Mechanisms whereby nerve growth factor increases diacylglycerol levels in differentiating PC12 cells.
Brain Res., 818:252-259, 1999.
Heterogeneous long chain Acyl-CoA synthetases control distribution of individual fatty acids in newly-formed glycerolipids of neuronal cells undergoing neurite outgrowth.
Neurochem. Res., 24(6):739-750, 1999.
The effects of tryptophan and tyrosine on human mood and performance.
Psychopharm. Bull., 20(3):595-598, 1984.
Mood, performance, and pain sensitivity: Changes induced by food constituents.
J. Psychiat. Res., 17(2):135-145, 1982.
The effects of dietary neurotransmitter precursors on human behavior.
Am. J. Clin. Nutri., 42:366-370, 1985.
Effects of melatonin on human mood and performance.
Brain Res., 323:201-207, 1984.
The effects of low doses of caffeine on human performance and mood.
Psychopharmacology, 92:308-312, 1987.
The effects of caffeine and aspirin onmood and performance.
J. Clin. Psychopharm., 75(5):315-320, 1987.
Foods and food constituents that affect the brain and human behavior.
Food Technology, 40(1):139-141, 1986.
Regional distribution of endogenous and parenteral glutamate, aspartate and glutamine in rat brain.
Biochem. Pharmacol., 26:443-446, 1977.
Serum tryptophan level after carbohydrate ingestion: Selective decline in non-albumin-bound tryptophan coincident with reduction in serum free fatty acids.
Life Sci., 12(II):57-64, 1973.
Stimulation of choline release from NG108-15 cells by 12-O-tetradecanoylphorbol 13-acetate.
Biochem. J., 241:81-86, 1987.
High-performance liquid chromatography of water-soluble choline metabolites.
Analyt. Biochem., 151:182-187, 1985.
Phosphatidylcholine biosynthesis in the neuroblastoma-glioma hybrid cell line NG108-15: Stimulation by phorbol esters.
J. Neurochem., 47(6):1936-1941, 1986.
Differential regulation of phosphatidylcholine biosynthesis by 12-O-tetradecanoylphorbol-13-acetate and diacylglycerol in NG108-15 neuroblastoma x glioma hybrid cells.
J. Biol. Chem., 262(36):17487-17491, 1987.
O-Methylation and decarboxylation of α-methyldopa in brain and spinal cord: Depletion of S-adenosylmethionine and accumulation of metabolites in catecholaminergic neurones.
Neuropharmacol., 15:395-402, 1976.
Differential effects of DSP-4 administration on regional brain norepinephrine turnover in rats.
Life Sci., 37:403-409, 1985.
Metabolism of cytidine (5')-diphosphocholine (CDP-choline) following oral and intravenous administration to the human and the rat.
Neurochem. Int., 11(3):293-297, 1987.
Effect of cytidine(5')diphosphocholine (CDP-choline) on the total urinary excretion of 3-methoxy-4-hydroxyphenylglycol (MHPG) by rats and humans.
J. Neural Trans., 66:129-134, 1986.
Evidence that 5'-Cytidinediphosphocholine can affect brain phospholipid composition by increasing choline and cytidine plasma levels.
J. Neurochem., 65(2):889-894, 1995.
Effects of orally administered cytidine 5'diphosphate choline on brain phospholipid content.
J. Nutr. Biochem., 3:313-315, 1992.
Enhancement by cytidine of membrane phospholipid synthesis.
J. Neurochem., 59(1):338-343, 1992.
Light intensities required to suppress nocturnal melatonin secretion in albino and pigmented rats.
Life Sci., 35:841-848, 1984.
Indirect effects of light: ecological and ethological considerations.
Annals New York Acad. Sci., 453:231-245, 1985.
Control of pineal indole biosynthesis by changes in sympathetic tone caused by factors other than environmental lighting.
Proc. Nat. Acad. Sci., 70(6):1704-1707, 1973.
The adrenal medulla may mediate the increase in pineal melatonin synthesis induced by stress, but not that caused by exposure to darkness.
Journal Neural Trans., 40:87-97, 1977.
Entrainment of rhythmic melatonin secretion in man to a 12-hour phase shift in the light/dark cycle.
Life Sci., 23:1557-1564, 1978.
Melatonin excretion of man and rats: Effect of time of day, sleep, pinealectomy and food consumption.
Int. Journal Biometeor., 19(4):267-279, 1975.
The measurement of melatonin in mammalian tissues and body fluids.
Journal Neural Trans., Suppl. 13:251-264, 1978.
Light intensity and the control of melatonin secretion in rats.
Neuroendocrinology, 33:181-185, 1981.
Artificial induction of melatonin rhythms by programmed microinfusion.
Neuroendocrin., 31:106-111, 1980.
Increase in rat pineal melatonin content following L-dopa administration.
Life Sci., 12(4):145-151, 1973.
Daily rhythm in human urinary melatonin.
Science, 187:169-171, 1975.
The effects of 6-hydroxydopamine pretreatment on the accumulation of dopa and dopamine in brain and peripheral organs following L-dopa administration.
Journal Neur. Trans., 33:63-71, 1972.
Long-term effects of postnatal 6-hydroxydopamine treatment on tissue catecholamine levels.
Journal Pharm. Exp. Ther., 183(1):56-64, 1972.
Blockade of endotoxin-induced hypothermia by pretreatment with intracisternal 6-hydroxydopamine.
Life Sci., 13:485-492, 1973.
Dietary carbohydrate increases brain tryptophan and decreases serum-free tryptophan.
Nature, 244(5410):34-35, 1973.
Relevance of free tryptophan in serum to tissue tryptophan concentrations.
Metabolism, 23(12):1107-1116, 1974.
Effects of ingesting soy or egg lecithins on serum choline, brain choline and brain acetylcholine.
J. Nutrition, 111(1):166-170, 1981.
Diurnal variations in plasma concentrations of basic and neutral amino acids and in red cell concentrations of aspartate and glutamate: effects of dietary protein intake.
Am. J. Clin. Nutr., 39:722-729, 1984.
Use of parenteral dipeptides to increase serum tyrosine levels and to enhance catecholamine-mediated neurotransmission.
Journal Pharm. Sci., 79(8):685-687, 1990.
Phentermine and other monoamine-oxidase inhibitors may increase plasma serotonin when given with fenfluramines.
The Lancet, 353(9146):38, 1999.
Does phentermine inhibit monoamine oxidase?.
The Lancet, 353(9161):1362-1363, 1999.
L-threonine administration increases glycine concentrations in the rat central nervous system.
Life Sci., 26:1283-1286, 1980.
High doses of aspartame reduce blood pressure in spontaneously hypertensive rats.
(Letter-to-the-Editor) New Eng. Journal Med., 309(18):1125, 1983.
Possible neurologic effects of aspartame, a widely used food additive.
Environmental Health Perspectives, 75:53-57, 1987.
Choline production from choline-containing phospholipids: A hypothetical role in Alzheimer’s Disease and aging.
Progr. Neuro- Psychopharmacol. & Biol. Psychiat., 8:637-642, 1984.
Effects of electrical stimulation and choline availability on the release and contents of acetylcholine and choline in superfused slices from rat striatum.
J. Physiol., 80:189-195, 1985.
Daily rhythm in the noradrenaline content of rat hypothalamus.
Nature, 217(5128):574-575, 1968.
Effects of ethanolamine (ETN) administration on ETN and choline (CH) levels in plasma, brain extracellular fluid (ECF) and brain tissue, and on brain phospholipid levels in rats: An in vivo study.
Neurosci. Res. Commun., 18(2):87-96, 1996.
Effect of choline on basal and stimulated acetylcholine release: an in vivo microdialysis study using a low neostigmine concentration.
Brain Res., 269:269-274, 1993.
Effect of various oral glucose doses on plasma neutral amino acid levels.
Metabolism, 31(9):937-943, 1982.
Role de l’alimentation dans la synthese des neurotransmetteurs of et dans les fonctions cerebrales: Implications cliniques.
Schweiz. Med. Wschr., 111:1422-1434, 1981.
Clonidine increases food and protein consumption in rats.
Life Sci., 27:781-791, 1980.
Co-administering tyrosine with glucose potentiates its effect on brain tyrosine levels.
Journal Neur. Trans., 55:317-321, 1982.
Monosodium glutamate neurotoxicity, hyperosmolarity, and blood-brain barrier dysfunction.
Neurobehavioral Toxicology, 1:279-283, 1979.
Blood-brain barrier transport of caffeine: Dose-related restriction of adenine transport.
Life Sci., 31:2079-2715, 1982.
Metabolic fuel and amino acid transport into the brain in experimental diabetes mellitus.
Proc. Natl. Acad. Sci., 79:5406-5410, 1982.
Entrainment of the body temperature rhythm in rats: Effect of color and intensity of environmental light.
Science, 181:956-957, 1973.
Neuronal expression of β-amyloid precursor protein Alzheimer mutations causes intracellular accumulation of a C-terminal fragment containing both the amyloid β and cytoplasmic domains.
Journal Biol. Chem., 272(40):24743-24746, 1997.
Plasma tyrosine in normal humans: Effects of oral tyrosine and protein-containing meals.
J. Neur. Trans., 47:299-306, 1980.
Serotonergic neurones are not involved in action of L-dopa in Parkinson’s disease.
Nature, 283:772-774, 1980.
Aromatic L-amino acid decarboxylase in rat corpus striatum: Implications for action of L-dopa in parkinsonism.
Neurology, 31(6):651-655, 1981.
Tyrosine administration increases striatal dopamine release in rats with partial nigrostriatal lesions.
Proc. Natl. Acad. Sci., 77(7):4305-4309, 1980.
L-3,4-dihydroxyphenylalanine and L-5-hydroxytryptophan decarboxylase activities in rat striatum: Effect of selective destruction of dopaminergic or serotoninergic input.
Journal Neurochem., 34(6):1753-1756, 1980.
Diminished decarboxylation of L-dopa in rat striatum after intrastriatal injections of kainic acid.
Neuropharmacology, 19:409-411, 1980.
Nonaminergic striatal neurons convert exogenous L-dopa to dopamine in Parkinsonism.
Annals of Neurology, 8(6):558-563, 1980.
Decarboxylation of exogenous L-DOPA in rat striatum after lesions of the dopaminergic neurons: The role of striatal capillaries.
Brain Res., 198:244-248, 1980.
Compensatory mechanisms in the nigrostriatal dopaminergic system in Parkinson’s disease: Studies in an animal model.
Israel Journal Medicinal Sci., 18:159-163, 1982.
The arrest of prolonged estrus in “middle-aged” rats by pineal gland extract.
Endocrin., 68(5):795-800, 1961.
Deanol acetamidobenzoate inhibits the blood-brain barrier transport of choline.
Annals Neurol., 4(4):302-306, 1978.
Lithium and brain choline levels.
New Eng. Journal Med., 300:196-197, 1979.
Choline administration elevates brain phosphorylcholine concentrations.
J. Neurochem., 38(6):1748-1752, 1982.
Choline and physostigmine enhance haloperidol-induced HVA and DOPAC accumulation.
Eur. Journal Pharm., 80:431-434, 1982.
Effects of phenylalanine on the release of endogenous dopamine from rat striatal slices.
Journal Neurochem., 47(5):1444-1448, 1986.
Dopamine synthesis in rat striatum: Mobilization of tyrosine from non-dopaminergic cells.
Experientia, 43(10):1109-1110, 1987.
Tyrosine availability determines stimulus-evoked dopamine release from rat striatal slices.
Neurosci. Letters, 59:215-220, 1985.
Release of endogenous dopamine from electrically stimulated slices of rat striatum.
Brain Res., 301:139-142, 1984.
Commentary: Catecholamine synthesis: Physiological coupling to precursor supply.
Biochem. Pharmacol., 35(6):875-881, 1986.
Effects of pineal compounds on mammals.
Life Sci., 17:1189-1200, 1975.
Report of Two Double-Blind Randomized Placebo-Controlled Pilot Studies of a Carbohydrate-Rich Nutrient Mixture for Treatment of Seasonal Affective Disorder (SAD).
CNS Neuroscience & Therapeutics , 16(20):13-24, 2010.
Regional tyrosine levels in rat brain after tyrosine administration.
Journal Neural Trans., 49:45-50, 1980.
Central Control of the pineal gland: Visual pathways.
Arch. Neurol., 18:208-218, 1968.
Visual pathway mediating pineal response to environmental light.
Science, 155(3759):220-223, 1967.
Characteristics of synaptosomal tyrosine uptake in various brain regions: Effect of other amino acids.
Life Sci., 28:65-75, 1981.
The ability of certain anorexic drugs to suppress food consumption depends on the nutrient composition of the test diet.
Life Sci., 35:1297-1300, 1984.
The pineal organ.
Spectrum, 21:1-6, 1978.
Attenuation by catecholamine antagonists of the hypothermia that follows cerebral infarction in gerbils.
Life Sci., 17:597-602, 1975.
The permissive role of hyperthermia in the disaggregation of brain polysomes by L-dopa or D-amphetamine.
Journal Neurochem, 28:779-782, 1977.
D-Amphetamine disaggregates brain polysomes via a dopaminergic mechanism.
Proc. Nat. Acad. Sci., 72(3):834-836, 1975.
Catecholamines and neurologic diseases.
New Eng. Journal Med., 293:274-280, 332-338, 1975.
Streptozotocin increases free fatty acids and decreases phospholipids in rat brain.
Journal Neural Transm., 105:1271-1281, 1998.
Insulin, plasma amino acid imbalance, and hepatic coma.
Lancet, 305:722-724, 1975.
Plasma neutral amino acids and tryptophan in cirrhosis.
Lancet, 2:419, 1975.
Inhibition of brain protein synthesis by doses of L-dopa that disaggregate brain polyribosomes.
J. Neur. Trans., 34:321-323, 1973.
Stimulation by artificial lighting of calcium absorption in elderly human subjects.
Nature, 229:255-257, 1971.
Phospholipid metabolite levels are altered in cerebral cortex of patients with dominantly inherited olivopontocerebellar atrophy.
Neurosci. Lett., 161:191-194, 1993.
Evidence for a membrane defect in Alzheimer disease brain.
Proc. Natl. Acad. Sci., 89:1671-1675, 1992.
Metabotropic glutamate receptor subtype mGluR1a stimulates the secretion of the amyloid ß-protein precursor ectodomain.
J. Neurochem., 69(2):704-712, 1997.
Serotonin 5-HT2a and 5-HT2c receptors stimulate amyloid precursor protein ectodomain secretion.
J. Biol. Chem., 271(8):4188-4194, 1996.
Release of amyloid ß-protein precursor derivatives by electrical depolarization of rat hippocampal slices.
Proc. Natl. Acad. Sci., 90:5191-5193, 1993.
Cerebrospinal fluid levels of amyloid β-protein in Alzheimer’s disease: Inverse correlation with severity of dementia and effect of apolipoprotein E genotype.
Ann. Neurol., 37(4):512-518, 1995.
Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors.
Science, 258:304-307, 1992.
Regulation of proteolytic processing of the amyloid ß-protein precursor by first messengers: A novel approach for the treatment of Alzheimer's disease.
Drug Res., 45(1):435-438, 1995.
A simple and rapid method for injecting H3-norepinephrine into the lateral ventricle of the rat brain.
Life Sci., 6:281-291, 1967.
Effect of dietary protein on urinary 5-hydroxyindoleacetic acid levels.
Journal Neurochem., 29:267-271, 1977.
Treatment of seasonal depression with d-fenfluramine.
J. Clin. Psychiatry, 50(9):343-347, 1989.
Aberrant Snacking Patterns and Eating Disorders in Patients With Obsessive Compulsive Disorder.
J. Clin. Psychiat., 55(10):445-447, 1994.
Effect of tyrosine on brain catecholamine turnover in reserpine-treated rats.
J. Neural Trans., 53:101-108, 1982.
Skeletal muscle: Reservoir for exogenous L-dopa.
J. Pharmacol. Exp. Ther., 190(1):187-191, 1974.
Enzymes catalyzing the de novo synthesis of methyl groups in the brain and other tissues of the rat.
J. Neurochem., 21:1447-1455, 1973.
Methylation of exogenous 3,4-dihydroxyphenylalanine (L-dopa)-effects on methyl group metabolism.
Biochem. Pharmacol., 191:134-137, 1973.
Folic acid deficiency and methyl group metabolism in rat brain: Effects of L-dopa.
Arch. Biochem. Biophys., 160:372-376, 1974.
In vitro neoplastic transformation of hamster pineal cells by three oncogenic DNA viruses.
Cancer, 21(3):477-482, 1968.
Melatonin in rat pineal, plasma, and urine: 24-hour rhythmicity and effect of chlorpromazine.
Endocrin., 98(6):1418-1424, 1976.
Melatonin secretion decreases during the proestrous stage of the rat estrous cycle.
Proc. Natl. Acad. Sci., 75(1):531-534, 1978.
Spectral power distribution of light sources affects growth and development of rats.
Photochem. Photobiol., 29:339-341, 1979.
Elevated intracellular calcium concentration increases secretory processing of the amyloid precursor protein by a tyrosine phosphorylation-dependent mechanism.
Biochem. J., 320:957-963, 1996.
D-amphetamine administration reduces Substance P concentration in the rat striatum.
Biochem. Pharmacol., 27:839-842, 1978.
d-amphetamine administration reduces Substance P concentration in the rat striatum.
Psychopharmacology Bulletin, 14:24-26, 1978.
Striatal substance P-like immunoreactivity: Characterization by high-performance liquid chromatography and aspects of subcellular distribution and in vitro release by potassium.
Life Sci., 27(17):1593-1602, 1980.
D-amphetamine reduces striatal substance P concentrations by presynaptic release of dopamine.
Brain Res., 186:409-419, 1980.
Serotonin, 5-hydroxyindoleacetic acid (5-HIAA), and monoamine oxidase in the bovine median eminence and pituitary gland.
Endocrin., 86(6):1460-1462, 1970.
Pituitary serotonin content: Effects of melatonin or deprivation of water.
Science, 169:285-286, 1970.
Adrenocortical Control of catecholamine metabolism in the dog adrenal medulla: Relationship to protein synthesis.
Endocrin., 93(3):566-574, 1973.
Mechanisms of changes in brain noreinephrine levels following olfactory bulb lesions.
Life Sci., 8(I):1309-1317, 1969.
Steroid induction of phenylethanolamine-N-methyl transferase in adrenomedullary explants: Independence of adrenal innvervation.
Endocrin., 86(6):1466-1468, 1970.
Effects of lighting on epinephrine synthesis in the rat.
Journal Neuro-Visceral Relations, 31:275-279, 1969.
Effects of endotoxin on monoamine metabolism in the rat.
Proc. Soc. Exp. Biol. Med., 140:739-746, 1972.
Enzymatic conversion of norepinephrine to epinephrine by the brain.
J. Pharmacol. Exp. Ther., 165(2):190-195, 1969.
Olfactory bulb removal: effects on brain norepinephrine.
Proc. Nat. Acad. Sci., 62(4):1052-1055, 1969.
Induction of epinephrine-forming enzyme by glucocorticoids: Steroid hydroxylation and inductive effect.
Nature, 219(5152):392-394, 1968.
Adrenocortical control of epinephrine synthesis.
Pharmacol. Rev., 23(1):1-35, 1971.
Prostaglandin E2 regulates amyloid precursor protein expression via the EP2 receptor in cultured rat microglia.
Neurosci. Letters, 362:127-130, 2004.
Uridine enhances neurite outgrowth in NGH-differentiated PC12 cells.
Neurosci., 134:206-214, 2005.
The 3-hydrox-3-methyglutary co-enzyme A reductase inhibitor pravastatin enhances neurite outgrowth in hippocampal neurons.
J. Neurochem., 97:716-723, 2006.
Relation between brain 5-HIAA levels and the release of serotonin into brain synapses.
Life Sci., 21:1741-1746, 1977.
Radial maze performance in three strains of mice: Role of the fimbria/fornix..
Brain Res., 263:172-176, 1983.
Tyrosine prevents behavioral and neurochemical correlates of an acute stress in rats.
Life Sci., 34:2225-2232, 1984.
Dietary tyrosine suppresses the rise in plasma corticosterone following acute stress in rats.
Life Sci., 37:2157-2163, 1985.
Diurnal changes in brain noradrenalin.
Life Sci., 7:91-98, 1968.
Effects of systemic nicotine on serotonin release in rat brain.
Brain Res., 621:311-318, 1993.
Stimulation of CDP-choline synthesis by uridine or cytidine in PC12 rat pheochromocytoma cells.
Brain Research, 971(2):161-167, 2003.
Base-exchange and cell growth in 3T6 mouse fibroblasts.
Biochimica et Biophysica Acta, 1127:99-102, 1992.
Polyunsaturated fatty acids stimulate phosphatidylcholine synthesis in PC12 cells.
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1771(4):558-563, 2007.
Effect of light intensity on regulation of melatonin secretion and drinking behavior in the albino rat.
Adv. Biosci., 29:119-121, 1981.
Relationship between light intensity and the melatonin and drinking rhythms or rats.
Neuroendocrinology, 37:155-160, 1983.
Effect of L-dopa pretreatment on in vivo protein synthesis in various rat brain regions.
Life Sci., 22(21):1887-1892, 1978.
In vivo inhibition of rat brain protein synthesis by d-amphetamine..
Journal Neurochem., 31:341-345, 1978.
In vivo inhibition of rat brain protein synthesis by L-dopa.
J. Neurochem., 23:233-239, 1974.
Regional effects of L-dihydroxyphenylalanine (L-dopa) on norepinephrine metabolism in rat brain.
Journal Pharm. Exp. Ther., 180(2):277-285, 1972.
Effects of L-Dopa administration on the concentrations of dopa, dopamine and norepinephrine in various rat tissues.
Journal Pharm. Exp. Ther., 184(1):67-72, 1973.
Daily rhythms in content and utilization of tyrosine in the whole mouse.
Nature, 226(5244):454-455, 1970.
The role of dietary protein in generating daily rhythms in rat liver tryptophan pyrrolase and tyrosine transaminase.
Metabolism, 22(9):1175-1184, 1973.
Morphologic changes in the pineal parenchyma cells of rats exposed to continuous light or darkness.
Endocrin., 71(6):888-892, 1962.
Physiological dependence of brain methionine and s-adenosylmethionine concentrations on serum amino acid pattern.
J. Neurochem., 23:227-231, 1974.
The effects of cholinergic agonists on apomorphine-induced stereotyped behavior in the rat.
Commun. Psychopharm., 2:255-262, 1978.
Low tryptophan diet decreases brain serotonin and alters response to apomorphine.
Nature, 279(5715):731-732, 1979.
Oral supplementation with docosahexaenoic acid and uridine 5'-monophosphate increases dendritic spine density in adult gerbil hippocampus.
Brain Research, 1182:50-59, 2007.
Coupling of transfected muscarinic acetylcholine receptor subtypes to phospholipase D.
J. Biol. Chem., 266(10):6031-6034, 1991.
Stimulation of phospholipase D activity in human neuroblastoma (LA-N-2) cells by activation of muscarinic acetylcholine receptors or by phorbol esters: relationship to phosphoinositide turnover.
Journal Neurochem., 56(4):1312-1319, 1991.
Effects of fluoxetine or D-fenfluramine on serotonin release from, and levels in, rat frontal cortex.
Brain Res., 529:294-301, 1990.
Effect of cytidine on membrane phospholipid synthesis in rat striatal slices.
J. Neurochem., 64(1):378-384, 1995.
The effect of a carbohydrate-rich beverage on mood, appetite, and cognitive function in women with premenstrual syndrome.
Obstet. Gynecol., 86(4):520-528, 1995.
Regional distribution of neurotransmitter-synthesizing enzymes and Substance P within the rat corpus striatum.
Brain Res., 143:556-560, 1978.
Choline administration to the rat increases urinary catecholamines.
Journal Neur. Trans., 43:103-112, 1978.
Tryptophan availability modulates serotonin release from rat hypothalamic slices.
J. Neurochem., 53(6):1925-1933, 1989.
Effect of chronic D-fenfluramine administration on rat hypothalamic serotonin levels and release.
Life Sci., 44:265-271, 1989.
Serotonin release varies with brain tryptophan levels.
Brain. Res., 532:203-210, 1990.
Efficacy of a medical food in mild Alzheimer's disease: a randomized controlled trial.
Alzheimer's and Dementia, 6:1-10, 2010.
Efficacy of Souvenaid in Mild Alzheimer's Disease: Results from a Randomized, Controlled Trial.
Journal of Alzheimer's Disease, 31:225-236, 2012.
Tyrosine administration decreases vulnerability to ventricular fibrillation in the normal canine heart.
Science, 211:727-729, 1981.
Enhancement of the anti-hypertensive effect of methyldopa and other anti-hypertensive drugs by carbidopa in spontaneously hypertensive rats.
Clin. Sci. and Molec. Med., 51:407s-410s, 1976.
Antihypertensive activity of metyrosine in spontaneously hypertensive rats and its enhancement by carbidopa.
Clin. Sci. Molec. Med., 55:255s-257s, 1978.
Lack of a direct effect of morphine on the synthesis of pineal 14C-indoles in organ culture.
Life Sci., 9(I):29-33, 1970.
Stimulation of [14C]Serotonin synthesis from [14C]tryptophan by mescaline in rat pineal organ cultures.
Life Sci., 10:273-282, 1971.
Synthesis of serotonin by pineal glands of the rat in organ culture.
Nature, 213(5077):730-731, 1967.
Cyclic adenosine monophosphate: Stimulation of melatonin and serotonin synthesis in cultured rat pineals.
Science, 166:519-520, 1969.
Stimulation of [14C]tryptophan 5-hydroxylation by norepinephrine and dibutyryl adenosine 3', 5', monophosphate in rat pineal organ cultures.
Life Sci., 10(1):935-940, 1971.
Perinatal undernutrition: Accumulation of catecholamines in rat brain.
Science, 171:1017-1019, 1971.
Effect of perinatal undernutrition on the metabolism of catecholamines in the rat brain.
Journal Nutrition, 103(11):1537-1547, 1973.
Phorbol ester stimulates choline uptake in Swiss 3T3 fibroblasts following introduction of the gene encoding protein kinase Ca.
Biochem. J., 305:621-626, 1995.
Rapid stimulation of amyloid precursor protein release by epidermal growth factor: Role of protein kinase C.
Biochem. J., 327:245-249, 1997.
Tyrosine phosphorylation-dependent stimulation of amyloid precursor protein secretion by the m3 muscarinic acetylcholine receptor.
Journal Biol. Chem., 270(14):8337-8344, 1995.
Production of diacylglycerol by exogenous phospholipase C stimulates CTP:Phosphocholine cytidylyltransferase activity and phosphatidylcholine synthesis in human neuroblastoma cells.
Journal Biochem. Chem., 266(36):24503-24508, 1991.
Pharmacology of memory disorders associated with aging, (Meeting Report).
Drug News and Perspectives, 4(4):236-240, 1991.
Uptake of exogenous phosphatidylserine by human neuroblastoma cells stimulates the incorporation of [methyl-14C]Choline into Phosphatidylcholine.
J. Neurochem., 53(2):472-481, 1989.
Regulation by phorbol esters of amyloid precursor protein release from Swiss 3T3 fibroblasts overexpressing protein kinase Ca.
J. Biol. Chem., 268(28):21097-21101, 1993.
Dioctanoylglycerol stimulates accumulation of [methyl-14C]choline and its incorporation into acetylcholine and phosphatidylcholine in a human cholinergic neuroblastoma cell line.
Brain Res., 585:169-176, 1992.
Regulation of synthesis and metabolism of the amyloid precursor protein by extracellular signals.
Research Progress in Alzheimer's Disease and Dementia ed. Miao-Kun Sun,Chpt. 1, pp. 1-29, 2006.
Serotonin binds specifically and saturably to an actin-like protein isolated from rat brain synaptosomes.
Proc. Natl. Acad. Sci., 81:959-963, 1984.
Binding of [3H]Serotonin to skeletal muscle actin.
Journal Neurochem., 45(3):819-824, 1985.
Association of serotonin, dopamine, or noradrenaline with an actin-like component in pheochromocytoma (PC12) cells.
Journal Neurochem., 45(3):825-831, 1985.
Neural and photic regulation of 5-hydroxytryptophan decarboxylase in the rat pineal gland.
Nature, 203(4948):981-982, 1964.
Control of 5-hydroxytryptophan decarboxylase activity in the rat pineal gland by sympathetic nerves.
J. Pharmacol. Exp. Ther., 147(3):371-375, 1965.
Effect of gonadal hormones on aromatic amino acid decarboxylase in the rat uterus.
Endocrin., 78(6):1135-1138, 1966.
The physiological disposition of C14-serotonin in the rat uterus.
Journal Pharm. Exp. Ther., 146(3):276-279, 1964.
Norepinephrine turnover in the heart and spleen of the cardiomyopathic Syrian hamster.
Circ. Res., 37:855-862, 1975.
Tyrosine hydroxylase activity in the heart of the cardiomyopathic Syrian hamster.
Journal Molec. Cell. Card., 9:225-233, 1977.
Neural control of dieting.
Nature, 380:488, 1996.
Citicoline improves verbal memory in aging.
Arch. Neurol., 53:441-448, 1996.
Effects of caffeine on anterior pituitary and thyroid function in the rat.
Journal Pharm. Exp. Ther., 214(1):58-62, 1980.
Characterization of neuropeptides by reversed-phase, ion-pair liquid chromatography with post-column detection by radioimmunoassay: Application to thyrotropin-releasing hormone, substance P, and vasopressin.
Journal Chromatog. Biomed. Applic., 222:381-387, 1981.
Reversed-phase, ion-pair separation of thyrotropin-releasing hormone and some analogs.
Journal Chromatography, 175:198-201, 1979.
TRH immunoreactivity in rat brain regions, spinal cord and pancreas: Validation by high-pressure liquid chromatography and thin-layer chromatography.
Brain Res., 201:279-288, 1980.
Formation and degradation of deamido-TRH (pyroglutamyl-histidyl- proine) in rat brain after intraventricular injection of TRH.
Brain Res., 216:343-350, 1981.
Thyrotropin-releasing hormone (TRH) content of rat striatum: Modification by drugs and lesions.
Brain Res., 216:323-331, 1981.
Neuroendocrine effects of caffeine in normal subjects.
Clin. Pharm. Therap., 36(3):402-407, 1984.
Increased TRH content of the basal ganglia in Huntington's disease.
New Eng. J. Med., 303:1235-1236, 1980.
Weight gain and withdrawal symptoms after smoking cessation: A preventive intervention using d-fenfluramine.
Health Psychol., 10(3):216-223, 1991.
Efficacies of dexfenfluramine and fluoxetine in preventing weight gain after smoking cessation.
Am. J. Clin. Nutr., 62:1181-1187, 1995.
Choline ingestion increases the resonance of choline-containing compounds in human brain: An in vivo proton magnetic resonance study.
Biol. Psychiatry, 37:170-174, 1995.
Melatonin concentrations in the sudden infant death syndrome.
Forensic Sci. Internat., 45:171-180, 1990.
Tyrosine administration reduces blood pressure and enhances brain norepinephrine release in spontaneously hypertensive rats.
Proc. Natl. Acad. Sci., 76(7):3511-3514, 1979.
Tyrosine administration decreases serum prolactin levels in chronically reserpinized rats.
Life Sci., 25(15):1293-1299, 1979.
Physiological disposition of oral piracetam in Sprague-Dawley rats.
Journal Pharm. Pharmacol., 36:659-662, 1984.
Rat brain phosphatidyl-N,N-dimethylethanolamine is rich in polyunsaturated fatty acids.
J. Neurochem., 45(3):805-809, 1985.
Phosphatidylcholine produced in rat synaptosomes by N-methylation is enriched in polyunsaturated fatty acids.
Proc. Natl. Acad. Sci., 82:4828-4831, 1985.
Chronic administration of UMP ameliorates the impairment of hippocampal-dependent memory in impoverished rats.
J. Nutr., 136:2834-2837, 2006.
Dietary cytidine (5')-diphosphocholine supplementation protects against development of memory deficits in aging rats.
Progress in Neuro-Psychopharm. & Biological Psychiatry, 27:711-717, 2003.
Dietary CDP-choline supplementation prevents memory impairment caused by impoverished environmental conditions in rats.
Learning and Memory, 12:39-43, 2005.
Inhibition of platelet-activating factor receptors in plasma membranes attenuates the inflammatory nociceptive response in rats.
Brain Research, 1097:230-233, 2006.
Platelet-activating factor increases prostaglandin E2 release from astrocyte-enriched cortical cell cultures.
Brain Res., 946(1):87-95, 2002.
Environmental conditions influence hippocampal-dependent behaviors and brain levels of amyloid precursor protein.
Eur. J. Neurosci., 16:2405-2415, 2002.
Platelet-activating factor antagonists decrease the inflammatory nociceptive response in rats.
Psychopharm., 163:430-433, 2002.
Platelet-activating factor affects nociception in rats at cerebral sites of action.
Cyclooxygenase-2 mediates platelet-activating factor-induced Prostaglandin E2 release from rat primary astrocytes.
Neuroscience Letters, 340:177-180, 2003.
Self-selection and regulation of protein: Carbohydrate ratio in foods adult rats eat.
Journal Nutr., 114:711-718, 1984.
A deficient binding mechanism for norepinephrine in hearts of scorbutic guinea pigs. (30754).
Proc. Soc. Exp. Bio. Med., 121:267-270, 1966.
Changes in blood osmolarity, electrolytes, and metabolites among adult rats treated with a neurotoxic dose of MSG.
Life Sci., 28:2855-2864, 1981.
N-methyl-d-aspartate increases acetylcholine release from rat striatum and cortex: Its effect is augmented by choline.
J. Pharm. Exp. Therap., 261(3):1122-1128, 1992.
Trans-synaptic induction of adrenomedullary tyrosine hydroxylase activity by choline: Evidence that choline administration can increase cholinergic transmission.
Proc. Natl. Acad. Sci., 74(2):798-800, 1977.
Characterization of phentermine and related compounds as monoamine oxidase (MAO) inhibitors.
Biochem. Pharm., 59:1611-1621, 2000.
Enhancement by choline of the induction of adrenal tyrosine hydroxylase by phenoxybenzamine, 6-hydroxydopamine, insulin or exposure to cold.
Journal Pharmacol. Exp. Ther., 204(3):676-682, 1978.
Cytidine and uridine increase striatal CDP-choline levels without decreasing acetylcholine synthesis or release.
Cellular and Molecular Neurobiology, Vol 26, Nos. 4-6:563-577, 2006.
Choline increases acetylcholine release and protects against the stimulation-induced decrease in phosphatide levels within membranes of rat corpus striatum.
Brain Res., 484:217-227, 1989.
Choline Administration: Activation of tyrosine hydroxylase in dopaminergic neurons of rat brain.
Science, 194:1060-1061, 1976.
Selective response of rat peripheral sympathetic nervous system to various stimuli.
J. Physiol., 293:513-523, 1979.
Prevention by choline of the depletion of membrane phosphatidylcholine by a cholinesterase inhibitor.
New Eng. Journal Med., 318(3):191, 1988.
Metabotropic glutamate receptor agonists increase release of soluble amyloid precursor protein derivatives from rat brain cortical and hippocampal slices.
J. Pharm. Exp. Ther., 281:149-154, 1997.
Effect of ACTH4-10 on the rate of synthesis of [3H]catecholamines in the brains of intact, hypophysectomized and adrenalectomized rats.
Brain Res., 93:522-557, 1975.
A Mg2+ dependent hydroxyindole 0-methyltransferase in rat harderian gland.
Biochim. Biophys. Acta, 261:194-197, 1972.
Concentrations of calcitonin and catecholamines in pheochromocytomas, a muscosal neuroma and medullary thyroid carcinoma.
Journal Clin. Endocrinol. Metab., 37(2):297-307, 1973.
Adenosine potentiates sympathomimetic effects of nicotinic agonists in vivo.
Journal Pharmacol. Exp. Ther., 236(2):344-349, 1986.
Adenosine strongly potentiates pressor responses to nicotine in rats.
Proc. Natl. Acad. Sci., 81:5599-5603, 1984.
Chronic caffeine consumption potentiates the hypotensive action of circulating adenosine.
Life Sci., 32:1151-1158, 1983.
A pharmacological dose of melatonin increases PRL levels in males without altering those of GH, LH, FSH, TSH, testosterone or cortisol.
Neuroendocrinology, 46:125-130, 1987.
Bioavailability of oral melatonin in humans.
Neuroendocrin., 39:307-313, 1984.
Fall in nocturnal serum melatonin during prepuberty and pubescence.
The Lancet, February 1984:362-365, 1984.
Amyloid precursor protein and membrane phospholipids in primary cortical neurons increase with development, or after exposure to nerve growth factor or Aß1-40.
Brain Res., 865:157-167, 2000.
Dietary supplementation with uridine-5'-monophosphate (UMP), a membrane phosphatide precursor, increases acetylcholine level and release in striatum of aged rat.
Brain Research, 1133:42-48, 2007.
Oral L-glutamine increases GABA levels in striatal tissue and extracellular fluid.
FASEB, 21:1227-1232, 2007.
Dietary uridine-5'-monophosphate supplementation increases potassium-evoked dopamine release and promotes neurite outgrowth in aged rats.
J. Molecular Neurosci, 27:137-145, 2005.
A Drosophila temperature-sensitive seizure mutant in phosphoglycerate kinase disrupts ATP generation and alters synaptic function.
Journal Neurosci., 24(19):4518-4529, 2004.
Carbidopa elevates hypothalamic dopa and serum prolactin in rats.
Life Sci., 24:1675-1682, 1979.
Participation of dopamine- and serotonin-receptors in the disaggregation of brain polysomes by L-dopa and L-5-HTP.
Journal Neurochem., 24:1191-1195, 1975.
L-dopa: Disaggregation of brain polysomes and elevation of brain tryptophan.
Science, 173:833-835, 1971.
Dopamine: Mediator of brain polysome disaggregation after L-Dopa.
Science, 177:613-616, 1972.
Disaggregation of brain polysomes by L-5-hydroxytryptophan: Mediation by serotonin.
Life Sci., 13:411-416, 1973.
Studies of the 24 hour rhythm of melatonin in man.
J. Neural Trans., Suppl. 13:325-337, 1978.
Viral neoplastic transformation of hamster pineal cells in vitro: Retention of enzymatic function.
Science, 154(3746):278-279, 1966.
Effect of nutrient intake on premenstrual depression.
Am. J. Obstet. Gynecol., 161(5):1228-1234, 1989.
The effect of a novel dietary intervention on weight loss in psychotropic drug-induced obesity.
Psychopharm. Bull., 36(3):55-59, 2002.
Prior carbohydrate consumption affects the amount of carbohydrate that rats choose to eat.
J. Nutr., 113:70-78, 1983.
Dexfenfluramine, fluoxetine, and weight loss among female carbohydrate cravers.
Neuropsychopharmacology, 9(3):201-210, 1993.
Carbohydrate craving in obese people: suppression by treatments affecting serotoninergic transmission.
Int. Journal Eating Dis., 1:2-15, 1981.
D-fenfluramine selectively suppresses carbohydrate snacking by obese subjects.
Int. J. Eating Disorders, 4(1):89-99, 1985.
Fenfluramine suppresses snack intake among carbohydrate cravers but not among noncarbohydrate cravers.
Int. Journal Eating Disorders, 6(6):687-699, 1987.
Fenfluramine and fluoxetine spare protein consumption while suppressing caloric intake by rats.
Science, 198:1178-1180, 1977.
Drugs that enhance central serotoninergic transmission diminish elective carbohydrate consumption by rats.
Life Sci., 24:895-904, 1979.
Sucrose consumption early in life fails to modify the appetite of adult rats for sweet foods.
Science, 205:321-322, 1979.
Fenfluramine and other serotoninergic drugs depress food intake and carbohydrate consumption while sparing protein consumption.
Current Med. Res. Opinion, 6:28-33, 1979.
Studies on the appetite for carbohydrates in rats and humans.
Journal Psychiat. Res., 17(2):213-221, 1982.
D-fenfluramine selectively decreases carbohydrate but not protein intake in obese subjects.
Int. Journal Obesity, 8(Suppl. 1):79-84, 1984.
Synapse formation and cognitive brain development: effect of docosahexaenoic acid and other dietary constituents.
Metabolism, 57(2):S6-S10, 2008.
Personalized medicine strategies for managing patients with Parkinsonism and cognitive deficits.
Metabolism Clinical and Experimental, 62:S27-S29, 2013.
Depression can beget obesity can beget depression.
An effect of luteinizing hormone on the fractional perfusion of the rat ovary.
Endocrin., 75(6):927-933, 1964.
Medical Progress: Catecholamines.
New Eng. J. Med., 273:637-646; 693-700, 746-753, 1965.
Control of epinephrine synthesis in the adrenal medulla by the adrenal cortex: Hormonal specificity and dose-response characteristics.
Endocrin., 79:608-614, 1966.
Ambiguities in the use of the term circadian.
Science, 156(3771):104, 1967.
Control of the synthesis and secretion of epinephrine (Editorial).
New Eng. Journal Med., 277:430, 1967.
Estrogen receptor: Ambiguities in the use of this term.
Science, 159:1261, 1968.
Biologic rhythms in the body.
Technology Review, 70(5):3-7, 1968.
The practical pharmacology of pheochromocytoma (Editorial).
New Eng. J. Med., 278:733, 1968.
Biological implications of artificial illumination.
Illuminating Engineering, Illumination Engineering Society, National Technical Conference, Phoenix, Arizona, September 8-12, 1968, 63:523-529, 1968.
Time-dependent variations in amino acid metabolism: mechanism of the tyrosine transaminase rhythm in rat liver.
Adv. Enzyme Regulation, 7:57-67, 1969.
The pineal gland in relation to reproduction.
Amer. Journal Obstet. Gynecol., 104(3):320-326, 1969.
The pineal and endocrine function.
Hospital Practice, 4(1):32-37, 1969.
Effetti biological del’illuminazione artificiale..
Diurnal rhythms in mammalian protein metabolism.
Mammalian Protein Metabolism (H.N. Munro, ed.) Academic Press, New York, Vol 4, Chapter 36, 1970.
Functions of the pineal in mammals.
Abbottempo, 3:30-33, 1970.
Effects of light on metabolic processes.
Birth Defects, Original Article Series, VI(2):60-62, 1970.
Editorial: Catecholamines and neurologic diseases.
New Eng. Journal Med., 282(1):45-46, 1970.
The pineal gland.
Res. in Reproduction, 3:3-4, 1971.
Biogenic amines and endocrine function. Introduction: Neuroendocrine transducers and monoamines.
Fed. Proc., 32(7):1769-1771, 1973.
Neuroendocrine transducers: Brain monoamines and the control of hypothalamo-pituitary function.
Psychopharmacol. Bulletin, 10:7-9, 1974.
Daily rhythms in tyrosine transaminase and other hepatic enzymes that metabolize amino acids: Mechanisms and possible consequences.
Life Sci., 15:827-847, 1974.
The effects of light on the human body.
Sci. Am., 233(1):69-77, 1975.
The effects of light on man and other mammals.
Ann. Rev. Physiol., 37:467-483, 1975.
In: Pediatrics. (A.M. Rudolph, ed.) Appleton-Century-Crofts, New York, pp.1693-1694, 1977.
Letters to the Editor: Paul Schrecker’s Philosophy: Changing norms: Before and after Kuhn.
Science, 297:514, 1977.
Food for thought.
The Sciences, 18:6-9, 1978.
Nutritional and precursor control of brain acetylcholine synthesis.
Psychopharm. Bulletin, 14:53-54, 1978.
Psychology Today, 12:140, 1978.
Physiological effects of melatonin.
Journal Neur. Trans., Suppl. 13:205- 207, 1978.
How diet affects the brain.
The pineal as a neuroendocrine transducer.
Hospital Practice, 467:82-92, 1980.
Meeting report: Workshop of the International Study Group (ISG) on the Pharmacology of Memory Disorders Associated with Aging.
The Pharmacologist, 22:72-75, 1980.
Meeting report: Workshop of the International Study Group (ISG) on the Pharmacology of Memory Disorders Associated with Aging.
Journal Neural Transmission, 47:319-325, 1980.
Trends in Neuroscience, 3:7-10, 1980.
The effects of nutritional factors on memory.
Acta Neurologica Scandinavica, 64:145-154, 1981.
A personal history of pineal research.
EPSG Newsletter, 7:12-19, 1982.
Nutrients that modify brain function.
Sci. Amer., 246(4):50-59, 1982.
Journal Psychiat. Res., 17(2):103-105, 1982.
Letter to the Editor: Myths about sugar myths.
Behavioural effects of nutrients.
Lancet, 1:1145-1147, 1983.
Cholinesterase inhibitors and opiate antagonists in patients with Alzheimer’s Disease.
New Eng. Journal Med., 309(9):555, 1983.
Neurochemical changes following high-dose aspartame with dietary carbohydrates.
New Eng. Journal Med., 390(7):429-430, 1983.
Stimulation of catecholamine secretion by choline.
Science, 222:188, 1983.
Invited comments on “Diet and Hyperkinesis”, by L.E. Arnold..
Integrative Psychiatry, 2:194-195, 1984.
The ultimate head waiter: How the brain controls diet.
Tech Review, 87:42-51, 1984.
Sci. Am., 252:62-74, 1985.
The medical and biological effects of light – Introductory remarks. In: Conference on Medical and Biological Effects on Light.
Ann. New York Acad. Sci., 453:ix-xi, 1985.
Melatonin as a hormone in humans: A history.
Yale Journal Biol. Med., 58:547-552, 1985.
Aspartame: Possible effect on seizure susceptibility.
The Lancet, 8463:1060, 1985.
Ways that food can affect the brain.
Nutrition Reviews, Diet and Behavior: A Multidisciplinary Evaluation, 44:2-6, 1986.
Serotoninergic drugs and carbohydrate snacking by obese carbohydrate cravers.
Strategies in the development of drugs that might be useful in cognitive disorders.
Clin. Neuropharmacol., 9(Suppl. 3):S3-S7, 1986.
Separate appetites for carbohydrates and proteins.
Medicographia, 8(2):27-30, 1986.
Effects of their nutrient precursors on the synthesis and release of serotonin, the catecholamines, and acetylcholine: Implications for behavioral disorders.
Clin. Neuropharm., 9(suppl.4):506-507, 1986.
Summary and forecast.
Ann. New York Acad. Sci., 494:343-348, 1987.
Aspartame effects on brain serotonin. Letter to the Editor..
Am. Journal Clin. Nutr., 45:799-801, 1987.
Nutrients affecting brain composition and behavior.
Integr. Psychiat., 5:226-257, 1987.
Dietary treatments that affect brain neurotransmitters: Effects on calorie and nutrient intake.
Ann. New York Acad. Sci., 499:179-190, 1987.
Circulating nutrients and neurotransmitter synthesis.
Journal Appl. Nutr., 39(1):6-28, 1987.
Why no testing of additives? (Op-Ed article).
Presynaptic control of release of amine neurotransmitters by precursor levels.
NIPS (Am. Physiol. Soc.), 3:158-163, 1988.
Effects of dietary amino acids, carbohydrates, and choline on neurotransmitter synthesis.
Mt. Sinai Journal Med., 55(1):75-86, 1988.
Effects of their nutrient precursors on the synthesis and release of serotonin, the catecholamines, and acetylcholine: Implications for behavioral disorders.
Clin. Neuropharm., 11(suppl.1):S187-S193, 1988.
Dexfenfluramine in the treatment of carbohydrate craving.
Medicographia, 10:28-30, 1988.
How the brain chooses foods based on their nutrient contents.
Letter to the Editor on THA-lecithin study.
New Eng. Journal Med., 323(13):919, 1990.
Jogging and light therapy.
Light Treatment and Biological Rhythms, 2(4):7-8, 1990.
Proceedings of Toxicology Forum, Given Institute, Aspen, CO, July 16-29:560-569, 1990.
Letter to the Editor: The choline-deficient diet.
FASEB J., 5:2612, 1991.
Choline metabolism as a basis for the selective vulnerability of cholinergic neurons.
Trends in Neurosci., 15(4):117-122, 1992.
Eating disorders associated with carbohydrate craving and affective symptoms: Mediation by brain serotonin.
Diabetes und Stoffwechsel, 2:449-453, 1993.
The return of the cholinergic hypothesis.
Journal Clin. Invest., 94:470, 1994.
CDP-choline: Pharmacological and clinical review – prologue.
Meth. Find. Exp. Clin. Pharamcol., 17(Suppl.B):iii-iv, 1995.
What went right: Why is HIV a treatable infection?.
Nature Med., 3(7):714-717, 1997.
The New Republic, November 10:16-18, 1997.
No DARPA for NIH.
Issues in Science and Technology, Summer:16, 1997.
Pharmacologic treatment of obesity.
Canadian Journal of Diagnosis, Supplement:12-14, 1997.
Letter-to-the-Editor: Dieter’s valve damage needs more research.
The MIT Encyclopedia of the Cognitive Sciences, MIT Press: 605-607, 1999.
La neurotoxicidad en la isquemia cerebral: del laboratorio a la clinica.
Rev. Neurol., 29(6):524-526, 1999.
Letter to the Editor: Tough medicine.
Boston Magazine, February:10-12, 2000.
Editorial: Age-related decreases in melatonin secretion—clinical consequences.
Journal Clin. Endocrin. Metab., 85(6):2135-2136, 2000.
Stress and the adrenocortical control of epinephrine synthesis.
Metabolism, 51(6, Suppl 1):11-14, 2002.
Letter to the Editor – “Applied path”.
New Republic, March 25:5, 2002.
Encyclopedia of Neuroscience, 3rd edition [on CD ROM] (G. Adelman, B.H. Smith, eds.) Elsevier Science, 2004.
Encyclopedia of Neuroscience, 3rd edition [on CD ROM] (G. Adelman, B.H. Smith, eds.) Elsevier Science, 2004.
The Clinical Research Center.
MIT Faculty Newsletter, Vol. XVI(4), February/March:18-20, 2004.
Genes, stress, and depression.
Metabolism, 54(1):16-19, 2005.
Curbside Consultation: Tossed in Translation.
Encyclopedia of Dietary Supplements (P. Coates, et al. eds), Marcel Dekker, Inc. (In Press, Galley Proof), 2005.
Narcolepsy and the hypocretins.
Metabolism:Clinical and Expermental, 55(Suppl 2):S36-S39, 2006.
Ramelteon, a novel treatment for the treatment of insomnia.
Expert Rev. Neurotherapeutics, 6(7):957-964, 2006.
Physiology and clinical use of melatonin.
UpToDate, April:1-24, 2006.
Letter to the Editor. FDA should regulate melatonin.
New York Times, January 23:D4, 2007.
Ramelteon: A melatonin receptor agonist.
Sleep Pharmacology: Basic Science and Clinical Applications, :, 2008.
For Boomers, it’s time to go to the brain gym. Letter to the Editor.
The New York Times, May 8:A30, 2008.
Fibromyalgia and the complex regional pain syndrome: Similarities in pathophysiology and treatment.
Metabolism Clinical and Experimental, 59(Suppl 1):S37-S40, 2010.
Enhancing synaptogenesis in diseases characterized by deficiencies in brain synapses.
Frontiers in Psychiatry, 1/Article 147:1-2, 2010.
Involvement of nutrients in the pathogenesis or management of Alzheimer’s disease.
US Neurology, 7(2):, 2011.
Non-nutritional uses of nutrients.
European Journal of Pharmacology, 668:S10-S15, 2011.
Personalized medicine strategies for managing patients with parkinsonism and cognitive deficits.
Use of melatonin to promote sleep.
U.S. Neurology, 8(1):10-, 2012.
This old turkey of a theory is depressingly inaccurate..
Wurtman, R.J. This old turkey of a theory is depressingly inaccurate.. , A15:None, 2013.
A nutrient combination that can affect synapse formation.
Nutrients, 6, doi:10.3390/nu6041701:1701-1710, 2014.
Biomarkers in the diagnosis and management of Alzheimers.
Low doses of melatonin promote sleep onset and maintenance in older people: An Update.
US Neurology, 10(2):117-119, 2014.
Neural systems and connectomics.
How anticholinergic drugs might promote Alzheimer's dementia: more A-beta and less phosphatidycholine..
Wurtman, R.J. How anticholinergic drugs might promote Alzheimer's dementia: more A-beta and less phosphatidycholine.. , 46:983-987, 2015.
Connectomics and Other Novel Methods for Examining Neural Systems.
Metabolism, 69:S13-S15, 2017.
The pineal gland and aldosterone.
Amer. Journal Physiol., 199(6):1109-1111, 1960.
Effects of pinealectomy and of a bovine pineal extract in rats.
Amer. J. Physiol., 197(1):108-110, 1959.
On the use of synthesis inhibitors to estimate brain norepinephrine synthesis in gonadectomized rats.
Life Sci., 8(Part I):1015-1022, 1969.
Distribution of the adrenaline-forming enzyme in the adrenal gland of a snake, Xenodon merremii.
Nature, 215(5103):879-880, 1967.
Medial forebrain bundle lesions: Blockade of effects of light on rat gonads and pineal.
Endocrin., 81(3):509-514, 1967.
Mediation of some effects of illumination on the rat estrous cycle by the sympathetic nervous system.
Endocrin., 75(2):266-272, 1964.
Photic and neural control of the 24-hour norepinephrine rhythm in the rat pineal gland.
J. Pharmacol. Exp. Ther., 157(3):487-492, 1967.
Changes in the enzymatic synthesis of melatonin in the pineal during the estrous cycle.
Endocrin., 76(4):798-800, 1965.
Demonstration of hydroxyindole-O-methyl transferase, melatonin, and serotonin in a metastatic parenchymatous pinealoma.
Nature, 204(4965):1323-1324, 1964.
Species differences in inducibility of phenylethanolamine-N-methyl transferase.
Endocrin., 82(3):584-590, 1968.
Inhibition of the metabolism of H3-melatonin by phenothiazines.
J. Pharmacol. Exp. Ther., 161(2):367-372, 1968.
Age and enzyme activity in the human pineal.
Journal Clin. Endocrin. Metab., 24:299-301, 1964.
Melatonin, a pineal substance: Effect on the rat ovary.
Science, 141(3577):277-278, 1963.
The relation between melatonin, a pineal substance, and the effects of light on the rat gonad.
Ann. New York Acad. Sci., 117:228-230, 1964.
Melatonin synthesis in the pineal gland: Effect of light mediated by the sympathetic nervous system.
Science, 143(3612):1328-1330, 1964.
Brain serotonin concentration: Elevation following intraperitoneal administration of melatonin.
Science, 162:277-278, 1968.
Uterine epinephrine and blood flow in pregnant and postparturient rats.
Endocrin., 73:501-503, 1963.
Melatonin synthesis in the pineal gland: Control by light.
Science, 142(3595):1071-1073, 1963.
The uptake of H3-melatonin in endocrine and nervous tissues and the effects of constant light exposure.
J. Pharmacol. Exp. Ther., 143(3):314-318, 1964.
The disposition of catecholamines in the rat uterus and the effect of drugs and hormones.
Journal Pharmacol. Exp. Ther., 144:150-155, 1964.
“Autocannibalism” of choline-containing membrane phospholipids in the pathogenesis of Alzheimer’s disease – a hypothesis.
Neurochem. Int., 7(2):369-372, 1985.
Facilitation of levodopa-induced dyskinesias by dietary carbohydrates.
New Eng. J. Med., 319:1288-1289, 1988.
Administration of docosahexaenoic acid, uridine and choline increases levels of synaptic membranes and dendritic spines in rodent brain. Omega-3 Fatty Acids, the Brain and Retina.
World Review of Nutrition and Dietetics (A.P. Simopoulos, N.G. Gazan, eds.), Karger, Basel, Vol. 99, pp. S153-S168, 2008.
Nutritional modifiers of aging brain function: increasing the formation of brain synapses by administering uridine and other phosphatide precursors.
Nutrition Reviews, 68(Suppl 2):S88-S101, 2010.
Use of phosphatide precursors to promote synaptogenesis.
Annual Reviews of Nutrition, 29:59-87, 2009.
Choline and its products acetylcholine and phosphatidylcholine.
Handbook of Neurochemistry, Vol. 8, Chpt. 3.2, pp._____, 2008.
Synapse formation is enhanced by oral administration of uridine and DHA, the circulating precursors of brain phosphatides.
The Journal of Nutrition, Health & Aging, 13(3):, 2009.
Impaired secretion of epinephrine in response to insulin among hypophysectomized dogs.
Proc. Nat. Acad. Sci., 61:522-528, 1968.
The fate of C14-dihydroxyphenylalanine (C14-Dopa) in the whole mouse.
J. Pharm. Exp. Therp., 174(3):351-356, 1970.
Daily rhythm in tyrosine concentration in human plasma: Persistence on low-protein diets.
Science, 158(3801):660-662, 1967.
Relation between the oestrous cycle and the binding of catecholamines in the rat uterus.
Nature, 198(4880):547-548, 1963.
Actions of l-epinephrine and related compounds.
Pharmacol. Exp. Ther., 127(4):281-287, 1959.
The Oxidative activity of blood serum in schizophrenic and manic- depressive psychoses.
A.M.A. Arch. Internal. Med., 102:790-794, 1958.
Nutritional needs of Parkinson’s patients.
Neurobiology of Aging, 2:149-151, 1981.
Precursor control of neurotransmitter synthesis.
Pharmacological Reviews, 32(4):315-335, 1980.
Thyroid function and the cardiac disposition of catecholamines.
Endocrin., 73:63-74, 1963.
Epinephrine and organ blood flow: Effects of hyperthyroidism, cocaine, and denervation.
Amer. J. Physiol., 207(6):1247-1250, 1964.
Formation of melatonin and 5-hydroxyindole acetic acid from 14C-tryptophan by rat pineal glands in organ culture.
Nature, 217(5132):953-954, 1968.
Brain catechol synthesis: Control by brain tyrosine concentration.
Science, 185:183-184, 1974.
Surgeon General’s Report on Nutrition and the Nervous System: Current Therapies and Future Directions.
Piracetam diminishes hippocampal acetylcholine levels in rats.
Life Sci., 28:1091-1093, 1981.
Valvulopathy or primary pulmonary hypertension as possible consequences of administering a serotonin uptake blocker with a monoamine oxidase inhibitor (“phen-fen”).
Cardiovascular Reviews and Reports, 20(6):312-314, 1999.
Inhibition of enzymatic synthesis of epinephrine by low doses of glucocorticoids.
Endocrin., 80:825-828, 1967.
Nutrient imbalances in depressive disorders: Possible brain mechanisms.
Ann. N.Y. Acad. Sci., 575:75-85, 1989.
Adrenocortical control of the biosynthesis of epinephrine and proteins in the adrenal medulla.
Pharmacol. Rev., 24(2):411-426, 1972.
Effect of oral CDP-choline on plasma choline and uridine levels in humans.
Biochem. Pharm., 60:989-992, 2000.
Daily rhythms in the concentrations of various amino acids in human plasma.
New Eng. J. Med., 279(4):171-175, 1968.
Daily rhythms in the concentrations of various amino acids in human plasma.
New Eng. Journal Med., 279(4):171-175, 1968.
L-Dihydroxyphenylalanine: Effect on S-adenosylmethionine in brain.
Science, 169:395-397, 1970.
Interactions of the pineal and exposure to continuous light on organ weights of female rats.
Acta Endocrinologica, 36:617-624, 1961.
Incorporation of 14C-tryptophan into 14C-protein by cultured rat pineals: Stimulation by i-norepinephrine.
Proc. Nat. Acad. Sci., 62(3):749-755, 1969.
Mediation by ß-adrenergic receptors of effects of norepinephrine on pineal synthesis of [14C]serotonin and [14C]melatonin.
J. Neurochem., 18:1683-1687, 1971.
Failure of brain norepinephrine depletion to extinguish the daily rhythm in hepatic tyrosine transaminase activity.
Nature, 219(5158):1049-1050, 1968.
Mechanism of the daily rhythm in hepatic tyrosine transaminase activity: Role of dietary tryptophan.
Proc. Nat. Acad. Sci., 59(3):800-807, 1968.
Synaptic Proteins and Phospholipids are Increased in Gerbil Brain by Administering Uridine Plus Docosahexaenoic Acid Orally.
Brain Research, 1088(1):83-92, 2006.
Use of choline in cholinergic neurons to form acetylcholine or phosphatidylcholine: Implications for the pathogenesis of age- related memory disorders.
Aging Brain and Dementia: New Trends in Diagnosis and Therapy, Alan R. Liss, Inc.: 215-238, 1990.
Effects of normal meals rich in carbohydrates or proteins on the plasma tryptophan ratio.
Am. J. Clin. Nutrition, 77:128-132, 2003.
Effects of normal meals rich in carbohydrates or proteins on the plasma tryptophan ratio.
Am. J. Clin. Nutrition, 77:128-132, 2003.
The mammalian pineal as a neuroendocrine transducer.
Recent Progr. Hormone Res., 25:493-522, 1969.
A sensitive and specific assay for the estimation of monoamine oxidase.
Biochem. Pharmacol., 12:1439-1440, 1963.
Sex steroids, cardiac 3H-Norepinephrine, and tissue monoamine oxidase levels in the rat.
Biochem. Pharmacol., 12:1417-1419, 1963.
Adrenaline synthesis: Control by the pituitary gland and adrenal glucocorticoids.
Science, 150(3702):1464-1465, 1965.
The pineal gland.
Sci. Amer., 213(1):50-60, 1965.
Control of Enzymatic synthesis of adrenaline in the adrenal medulla by adrenal cortical steroids.
J. Biol. Chem., 241(10):2301-2305, 1966.
Effect of chlorpromazine and other drugs on the disposition of circulating melatonin.
Nature, 212(5059):312, 1966.
A 24-hour rhythm in the content of norepinephrine in the pineal and salivary glands of the rat.
Life Sci., 5:665-669, 1966.
The physiologic effects of melatonin and the control of its biosynthesis.
Problemes Actuels d’Endocrinologie et de Nutrition, 10:189-200, 1966.
Daily rhythmic changes in the tyrosine transaminase of the rat liver.
Proc. Nat. Acad. Sci., 57(6):1594-1598, 1967.
The formation, metabolism, and physiologic effects of melatonin.
Advances in Pharmacology, 6A:141-151, 1968.
The slowing of treatment discover, 1965-1995.
Nature Med., 1(11):1122-1125, 1995.
Taking Issue: Training the students who will discover treatments for psychiatric diseases.
Psychiatric Res. Reports, 12(2):6-7, 1996.
Effects of the diet of brain neurotransmitters.
Nutrition Rev., 32(7):193-200, 1974.
Control of brain neurotransmitter synthesis by precursor availability and nutritional state.
Biochem. Pharmacol., 25:1691-1696, 1976.
Efectos neuroendocrinos de las drogas psicotropicas.
Tribuna Medica, 34:13-20, 1976.
Normal effects of nutrients on the brain.
Nourishing our neurons.
Science Year, World Book, Childcraft International, Inc., Chicago: 86-97, 1980.
Control of brain monoamine synthesis by diet and plasma amino acids.
Am. J. Clin. Nutr., 28:638-647, 1975.
Dietary enhancement of CNS neurotransmitters.
Hospital Practice, 13:71-77, 1978.
Lecithin consumption raises serum-free-choline levels.
Lancet, II:68-69, 1977.
Melatonin synthesis by an ectopic pinealoma.
New Eng. Journal Med., 274:1233-1237, 1966.
A sensitive and specific isotopic assay for the estimation of tyrosine transaminase.
Biochem. Pharm., 17:817-818, 1968.
Melatonin secretion as a mediator of circadian variations in sleep and sleepiness.
Integr. Psychiat., 5:13-14, 1987.
Melatonin secretion as a mediator of circadian variations in sleep and sleepiness.
Journal Pineal Res., 2:301-303, 1985.
Surgeon General’s Report on Nutrition and Health: Behavioral Disorders.
CDP-colina, neurotransmisores y metabolismo de fosfolipidos.
Medicina Clinica, 87(Suppl. 1):3-4, 1986.
Strategies for assessing the effects of food additives on the brain and behavior.
Fundamental and Applied Toxicology, 4:S318-S322, 1984.
Effects of oral aspartame on plasma phenylalanine in humans and experimental rodents.
Journal Neural Trans., 70:169-173, 1987.
The Fifth Annual Foster Elting Bennett Memorial Lecture: Brain catecholamines and neurological disease.
Trans. Am. Neurol. Assn., 99:49-60, 1974.
The pineal organ.
New Eng. Journal Med., 296:1329-1333 & 1383-1386, 1977.
Editorial: Good light and bad.
New Eng. J. Med., 282:394-395, 1970.
Physiological control of melatonin synthesis and secretion: Mechanisms generating rhythms in melatonin, methoxytryptophol, and arginine vasotocin levels and effects on the pineal of endogenous catecholamines, the estrous cycle, and environmental lighting.
Journal Neural Trans., 13:59-70, 1978.
Summary: Circulating tryptophan, brain tryptophan, and psychiatric disease.
Journal Neural Trans., Suppl. 15:227-236, 1979.
Effects of levodopa on nondopaminergic brain neurons.
Neurology, 22(5)/2:72-81, 1972.
Lack of effect of increased pineal serotonin content on H3-tryptophan uptake.
Journal Neur. Trans., 36:177-181, 1975.
Letter to the Editor.
New Eng. Journal Med., 302(26):1483, 1980.
Suppression of noradrenaline synthesis in sympathetic nerves by carbidopa, an inhibitor of peripheral dopa decarboxylase.
Nature, 265(5589):79-80, 1977.
Environmental lighting and neuroendocrine function: Relationship between spectrum of light source and gonadal growth.
Endocrinology, 85(6):1218-1221, 1969.
Nutrients, neurotransmitter synthesis, and the control of food intake.
Psychiatric Annals, 13:854-857, 1983.
Carbohydrate craving, obesity and brain serotonin.
Appetite, 7 (Supplement):99-103, 1986.
Do carbohydrates affect food intake via neurotransmitter activity?.
Appetite, 11(Suppl.):42-47, 1988.
Carbohydrates and depression.
Sci. Am., 260(1):68-75, 1989.
Brain serotonin, carbohydrate-craving, obesity and depression.
Obesity Res., Vol. 3(Suppl.):477S-492S, 1995.
Serotoninergic mechanisms and obesity.
Journal Nutr. Biochem., 9:511-515, 1998.
Nutrition and the Brain.
Nutrition and the Brain.
Nutrition and the Brain, Raven Press, New York, vol. 7: v-vii, 1986.
Monoamine neurotransmitters and the pathophysiology of stroke and central nervous system trauma.
J. Neurosurgery, 40(1):34-36, 1974.
Improvement of sleep quality by melatonin.
The Lancet, 346(8988):1491, 1995.
Letter to the Editor: Oral melatonin in neurologically disabled children.
The Lancet, 351(9120):1963-1964, 1998.
Pharmacologic tools in autonomic nervous system research.
Anesthesiology, 29:714-723, 1968.
Physiology and clinical use of melatonin.
A nutrient combination that can affect synapse formation.
Release of brain dopamine as the probable mechanism for the hypothermic effect of D-amphetamine.
Nature, 240(5382):477-478, 1972.
The effects of d-amphetamine and related drugs on colonic temperatures of rats kept at various ambient temperatures.
Life Sci., 11(I):851-859, 1972.
Paradoxical thermoregulatory behavior in rats induced by (+)-amphetamine: Blockade by α-adrenoceptor or dopamine receptor blocking agents.
Journal Pharm. Pharmac., 26:210-212, 1974.
Paradoxical effects of d-amphetamine on behavioral thermoregulation: possible mediation by brain dopamine.
Journal Pharmacol. Exp. Ther., 190(1):118-122, 1974.
Dopaminergic neurons in the nigro-striatal and mesolimbic pathways: Mediation of specific effects of d-amphetamine.
Endocrin., 97(5):154-158, 1975.
Selection of dietary protein and carbohydrate by rats: Changes with maturation.
Physiol. & Behavior, 36:979-982, 1986.
Meal composition and plasma amino acid ratios: Effect of various proteins or carbohydrates, and of various protein concentrations.
Metabolism, 35(9):837-842, 1986.
Acute effects of oral or parenteral aspartame on catecholamine metabolism in various regions of rat brain.
Journal Nutr., 116:356-364, 1986.
Intracellular and cell-surface distribution of amyloid precursor protein in cortical astrocytes.
Brain Res. Bull., 50(1):27-32, 1999.
A prospective study of sexual development and growth in American girls: The statistics of menarche.
Obstet. & Gyn. Survey, 31(4):325-337, 1976.
Sexual maturation in contemporary American girls.
Amer. J. Obstet. Gynecol., 108(5):833-846, 1970.
Blindness: Its relation to age of menarche.
Science, 144(3622):1154-1155, 1964.
Age at menarche: Genetic and environmental influences.
New Eng. J. Med., 280:868-875, 1969.
Blindness and menarche.
Obstet. Gynecol., 33(5):603-608, 1969.
Mechanism of action of methyldopa in the rat.
Circ. Res., 45(5):684-690, 1979.
Effects of neutral amino acids on the antihypertensive action of methyldopa in spontaneously hypertensive rats.
J. Pharm. Pharmacol., 30:60-62, 1978.
Cholinergic neurones and memory.
Nature, 293:187-188, 1982.
Elevated choline concentration in neonatal plasma.
Life Sci., 26:1827-1831, 1980.
Normal plasma choline responses to ingested lecithin.
Neurology, 30(11):1226-1229, 1980.
Developmental changes in brain indoles, serum tryptophan and other serum neutral amino acids in the rat.
Dev. Brain Res., 1:551-564, 1981.
Memory disorders associated with aging.
TINS, 24:VIII-IX, 1981.
Choline content of mothers' milk in Ecuador and Boston.
New Eng. J. Med., 306(3):175-176, 1982.
Uptake of free choline by isolated perfused rat liver.
Proc. Natl. Acad. Sci., 77(8):4417-4419, 1980.
Developmental changes in rat blood choline concentration.
Biochem. J., 198:565-570, 1981.
Neurogenic regulation of cerebral blood flow following ischemia.
Stroke, 7(2):113-118, 1976.
Reduction in brain dopamine following experimental cerebral ischemia.
Nature, 247(5439):283-284, 1974.
Edogenous melatonin levels and the fate of exogenous melatonin: Age effects.
J. Gerontology, 53A(4):B293-B298, 1998.
How does melatonin affect sleep?.
Harvard Med. Ltr., 12(6):8, 1996.
Behavioral effects of melatonin treatment in non-human primates.
Sleep Research Online, 1(3):114-118, 1998.
Melatonin: A sleep-promoting hormone.
Sleep, 20(10):899-907, 1997.
Sleep-inducing effects of low doses of melatonin ingested in the evening.
Clin. Pharm. Therap., 57(5):552-558, 1995.
Effects of low oral doses of melatonin, given 2-4 hours before habitual bedtime, on sleep in normal young humans.
Sleep, 19(5):423-431, 1996.
Melatonin treatment for age-related insomnia.
J. Clin. Endocrin. Metab., 86(10):4727-4730, 2001.
Effects of a low dose of melatonin on sleep in children with Angelman syndrome.
J. Ped. Endocrin. Metab., 12:57-67, 1999.
Efficacy of melatonin as a sleep-promoting agent.
J. Biol. Rhythms, 12(6):644-650, 1997.
Effect of lateral hypothalamic lesions of uptake of norepinephrine by brain homogenates.
Journal Pharm. Exp. Ther., 179(1):20-28, 1971.
Telemetric methods in pharmacology: Telemetric measurement of effects of light and drugs on diurnal body temperature rhythms.
Proc. Fourth Int. Cong. Pharm., 5:279-287, 1970.
Hepatic tyrosine transaminase rhythm: Interaction of environmental lighting, food consumption and dietary protein content.
J. Nutrition, 98(1):71-75, 1969.
Daily rhythm in the accumulation of brain catecholamines synthesized from circulating H3-tyrosine.
Journal Pharm. Exp. Ther., 172:416-422, 1970.
Brain 3H-catechol synthesis and the vaginal estrous cycle.
Neuroendocrine, 11:144-149, 1973.
Plasma choline concentration varies with different dietary levels of vitamins B6, B12 and folic acid in rats maintained on choline-adequate diets.
British Journal of Nutrition, 107:1408-1412, 2012.
Combined dietary folate, vitamin B-12, and vitamin B-6 intake influences plasma docosahexaenoic acid concentration in rats.
Nutrition & Metabolism, 9:49 :doi:10.1186/1743-7075-9-49, 2012.